Functional genomics using high-throughput RNA interference (Q33211852)

24 July 2017

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title

Functional genomics using high-throughput RNA interference (English)

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24 July 2017

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Dominique Vanhecke

1

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24 July 2017

Michal Janitz

series ordinal

2

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24 July 2017

publication date

1 February 2005

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24 July 2017

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24 July 2017

volume

10

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24 July 2017

issue

3

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24 July 2017

page(s)

205-212

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describes a project that uses

24 July 2017

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Microarrays of cells expressing defined cDNAs

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Surfection: a new platform for transfected cell arrays

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Microarray transfection analysis of transcriptional regulation by cAMP-dependent protein kinase

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Conditional gene targeting

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Initiation and maintenance of virus-induced gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

RNA-directed de novo methylation of genomic sequences in plants.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Transcriptional silencing and promoter methylation triggered by double-stranded RNA

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A biochemical framework for RNA silencing in plants

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Managing the genome: microRNAs in Drosophila.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Prediction of mammalian microRNA targets

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

1 reference

7 January 2021

Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

RNAi in C. elegans: soaking in the genome sequence

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Genetic requirements for inheritance of RNAi in C. elegans

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Inducible systemic RNA silencing in Caenorhabditis elegans

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Genome-wide RNAi analysis of growth and viability in Drosophila cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

How cells respond to interferons

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Enzymatic production of RNAi libraries from cDNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Effective expression of small interfering RNA in human cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A resource for large-scale RNA-interference-based screens in mammals.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Killing the messenger: short RNAs that silence gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Stable suppression of tumorigenicity by virus-mediated RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

1 reference

7 January 2021

Noise amidst the silence: off-target effects of siRNAs?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Expression profiling reveals off-target gene regulation by RNAi

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Specificity of short interfering RNA determined through gene expression signatures

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Induction of an interferon response by RNAi vectors in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Activation of the interferon system by short-interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Induction of DNA methylation and gene silencing by short interfering RNAs in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Gene silencing in mammals by small interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

High-throughput selection of effective RNAi probes for gene silencing.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A novel approach for evaluating the efficiency of siRNAs on protein levels in cultured cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

RNAi microarray analysis in cultured mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Interference of hepatitis C virus RNA replication by short interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Selecting protein tyrosine phosphatases as drug targets

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

The discovery of receptor tyrosine kinases: targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Induction of apoptosis in tumor cells by siRNA-mediated silencing of the livin/ML-IAP/KIAP gene

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

CORG: a database for COmparative Regulatory Genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A public gene trap resource for mouse functional genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

An approach to genomewide screens of expressed small interfering RNAs in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Restriction enzyme-generated siRNA (REGS) vectors and libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Generation of an shRNAi expression library against the whole human transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

A plasmid-based system for expressing small interfering RNA libraries in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

Small interfering RNA production by enzymatic engineering of DNA (SPEED)

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903352-5

7 January 2021

10.1016/S1359-6446(04)03352-5

Identifiers

DOI

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24 July 2017

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