Practical strategies for discovering regulatory DNA sequence motifs (Q33242798)

24 July 2017

Practical strategies for discovering regulatory DNA sequence motifs (English)

1 reference

24 July 2017

Ernest Fraenkel

2

0 references

author name string

Kenzie D MacIsaac

series ordinal

1

1 reference

24 July 2017

1 April 2006

1 reference

PLOS Computational Biology

24 July 2017

1 reference

24 July 2017

2

1 reference

24 July 2017

4

1 reference

24 July 2017

e36

1 reference

Creative Commons Attribution 4.0 International

24 July 2017

start time

28 April 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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21 June 2018

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21 June 2018

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A hypothesis-based approach for identifying the binding specificity of regulatory proteins from chromatin immunoprecipitation data.

21 June 2018

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Limitations and potentials of current motif discovery algorithms

21 June 2018

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21 June 2018

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21 June 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

21 June 2018

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21 June 2018

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21 June 2018

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A high-resolution map of active promoters in the human genome

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21 June 2018

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WordSpy: identifying transcription factor binding motifs by building a dictionary and learning a grammar

21 June 2018

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Mining ChIP-chip data for transcription factor and cofactor binding sites

21 June 2018

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De novo cis-regulatory module elicitation for eukaryotic genomes

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A boosting approach for motif modeling using ChIP-chip data

21 June 2018

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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

21 June 2018

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A Gibbs sampler for identification of symmetrically structured, spaced DNA motifs with improved estimation of the signal length.

21 June 2018

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DIP-chip: rapid and accurate determination of DNA-binding specificity.

21 June 2018

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Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach

21 June 2018

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Genome-wide regulatory complexity in yeast promoters: separation of functionally conserved and neutral sequence

21 June 2018

1 reference

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Making connections between novel transcription factors and their DNA motifs.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Assessing computational tools for the discovery of transcription factor binding sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

MONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary model

21 June 2018

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PhyME: a probabilistic algorithm for finding motifs in sets of orthologous sequences

21 June 2018

1 reference

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Decoding human regulatory circuits

21 June 2018

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Bipartite pattern discovery by entropy minimization-based multiple local alignment.

21 June 2018

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Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura

21 June 2018

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Transcriptional regulatory code of a eukaryotic genome

21 June 2018

1 reference

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Combinatorial control of gene expression.

21 June 2018

1 reference

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CisModule: de novo discovery of cis-regulatory modules by hierarchical mixture modeling

21 June 2018

1 reference

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Identifying combinatorial regulation of transcription factors and binding motifs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

MotifPrototyper: a Bayesian profile model for motif families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Eukaryotic regulatory element conservation analysis and identification using comparative genomics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Detection of functional DNA motifs via statistical over-representation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Use of chromatin immunoprecipitation assays in genome-wide location analysis of mammalian transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Whole-genome discovery of transcription factor binding sites by network-level conservation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Combining phylogenetic data with co-regulated genes to identify regulatory motifs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

A biophysical approach to transcription factor binding site discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Position specific variation in the rate of evolution in transcription factor binding sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Finding Functional Features in Saccharomyces Genomes by Phylogenetic Footprinting

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Identification of conserved regulatory elements by comparative genome analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Sequencing and comparison of yeast species to identify genes and regulatory elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Greedy mixture learning for multiple motif discovery in biological sequences.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Identification of co-regulated genes through Bayesian clustering of predicted regulatory binding sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Integrating regulatory motif discovery and genome-wide expression analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Toucan: deciphering the cis-regulatory logic of coregulated genes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Rank order metrics for quantifying the association of sequence features with gene regulation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Additivity in protein-DNA interactions: how good an approximation is it?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

An algorithm for finding protein-DNA binding sites with applications to chromatin-immunoprecipitation microarray experiments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Finding motifs using random projections

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Nucleotides of transcription factor binding sites exert interdependent effects on the binding affinities of transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Identifying regulatory networks by combinatorial analysis of promoter elements

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Non-independence of Mnt repressor-operator interaction determined by a new quantitative multiple fluorescence relative affinity (QuMFRA) assay.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

BioProspector: discovering conserved DNA motifs in upstream regulatory regions of co-expressed genes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Regulatory element detection using correlation with expression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

An overview of the structures of protein-DNA complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Mining for putative regulatory elements in the yeast genome using gene expression data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Building a dictionary for genomes: identification of presumptive regulatory sites by statistical analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

DNA binding sites: representation and discovery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Identifying DNA and protein patterns with statistically significant alignments of multiple sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Structure and function of the interferon-beta enhanceosome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Methods and statistics for combining motif match scores

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Searching for regulatory elements in human noncoding sequences.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Assessing test accuracy and its clinical consequences: a primer for receiver operating characteristic curve analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

The value of prior knowledge in discovering motifs with MEME

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Use of the ‘Perceptron’ algorithm to distinguish translational initiation sites inE. coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Methods for calculating the probabilities of finding patterns in sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Nomenclature for incompletely specified bases in nucleic acid sequences: recommendations 1984.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Sequence logos: a new way to display consensus sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Critical comparison of consensus methods for molecular sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Stochastic Relaxation, Gibbs Distributions, and the Bayesian Restoration of Images

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Finding motifs with insufficient number of strong binding sites.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Combining phylogenetic motif discovery and motif clustering to predict co-regulated genes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Improved detection of DNA motifs using a self-organized clustering of familial binding profiles.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

TAMO: a flexible, object-oriented framework for analyzing transcriptional regulation using DNA-sequence motifs.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Transcription factor binding site identification using the self-organizing map.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Logos: a modular bayesian model for de novo motif detection.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Predicting gene expression from sequence.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Constrained binding site diversity within families of transcription factors enhances pattern discovery bioinformatics.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Negative information for motif discovery.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Phylogenetic motif detection by expectation-maximization on evolutionary mixtures.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

BioOptimizer: a Bayesian scoring function approach to motif discovery.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Modeling within-motif dependence for transcription factor binding site predictions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

31 October 2018

Discriminative motifs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Identification of regulatory elements using a feature selection method.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Separating real motifs from their artifacts.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

Human-mouse genome comparisons to locate regulatory sites

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

The statistical significance of nucleotide position-weight matrix matches.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

A Discriminative Model for Identifying Spatial cis-Regulatory Modules

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1447654

BEST: binding-site estimation suite of tools

31 October 2018

1 reference

12 December 2020

Identifying target sites for cooperatively binding factors

1 reference

12 December 2020

Finding composite regulatory patterns in DNA sequences

1 reference

12 December 2020

An algorithm for finding signals of unknown length in DNA sequences

1 reference

12 December 2020

10.1371/JOURNAL.PCBI.0020036

Identifiers

DOI

1 reference

journals/ploscb/MacIsaacF06

24 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

24 July 2017

1 reference

PubMed ID

16683017