Short interfering RNA (siRNA) as a novel therapeutic (Q33243420)

24 July 2017

1 reference

retracted paper

2 references

Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

Short interfering RNA (siRNA) as a novel therapeutic (English)

1 reference

24 July 2017

Peter N Pushparaj

1

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author name string

Alirio J Melendez

series ordinal

2

1 reference

24 July 2017

1 May 2006

1 reference

Clinical and Experimental Pharmacology and Physiology

24 July 2017

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24 July 2017

33

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24 July 2017

504-510

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24 July 2017

5-6

1 reference

RNA-dependent RNA polymerases, viruses, and RNA silencing

24 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Heritable gene silencing in Drosophila using double-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Double-stranded RNA injection produces null phenotypes in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Functional genomics and target validation approaches using antisense oligonucleotide technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA as a drug target: methods for biophysical characterization and screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNAi: nature abhors a double-strand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNAi in human cells: basic structural and functional features of small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

MicroRNA maturation: stepwise processing and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

miRNP:mRNA association in polyribosomes in a human neuronal cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Role of microRNAs in plant and animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference: the silent treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Unlocking the potential of the human genome with RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Intravascular adenoviral agents in cancer patients: lessons from clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Electroporation and RNA interference in the rodent retina in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Caspase 8 small interfering RNA prevents acute liver failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Lack of efficacy of 'naked' small interfering RNA applied directly to rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference in mammalian cells by chemically-modified RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

siRNAs: applications in functional genomics and potential as therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference: gene silencing in the fast lane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Small RNA: can RNA interference be exploited for therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Therapeutic gene silencing in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Molecular medicine for the brain: silencing of disease genes with RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

BACE1 Suppression by RNA Interference in Primary Cortical Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Transient siRNA-mediated attenuation of liver expression from an alpha-galactosidase A plasmid reduces subsequent humoral immune responses to the transgene product in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Short interfering RNA confers intracellular antiviral immunity in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Modulation of HIV-1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Interference of hepatitis C virus RNA replication by short interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Inhibition of hepatitis C virus protein expression by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Allele-specific silencing of dominant disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

How cells respond to interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Interfering with disease: opportunities and roadblocks to harnessing RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Cell microarrays and RNA interference chip away at gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Inducible shRNA expression for application in a prostate cancer mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Pharmaceutical prospects for RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Short interfering RNA-directed inhibition of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

RNA interference targeting Fas protects mice from fulminant hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2006.04399.X

X-ray crystallographic and site-directed mutagenesis analysis of the mechanism of Schiff-base formation in phosphonoacetaldehyde hydrolase catalysis

21 January 2018

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1111/J.1440-1681.2006.04399.X

siRNA-directed inhibition of HIV-1 infection

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1111/J.1440-1681.2006.04399.X

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1111/J.1440-1681.2006.04399.X

Gene targeting via triple-helix formation

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1111/J.1440-1681.2006.04399.X

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.1111/J.1440-1681.2006.04399.X

Identifiers

DOI

10.1111/J.1440-1681.2006.04399.X

1 reference

24 July 2017

1 reference

PubMed ID

16700886