Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon (Q33289262)

25 July 2017

title

Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon (English)

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25 July 2017

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Daniel D Christensen

1

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25 July 2017

publication date

1 January 2007

1 reference

Primary Care Companion to the Journal of Clinical Psychiatry

25 July 2017

published in

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25 July 2017

volume

9

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25 July 2017

issue

1

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25 July 2017

page(s)

32-41

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Safety, tolerability, pharmacokinetics, and Abeta levels after short-term administration of R-flurbiprofen in healthy elderly individuals

25 July 2017

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Lessons from the AN 1792 Alzheimer vaccine: lest we forget.

14 July 2018

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14 July 2018

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

14 July 2018

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14 July 2018

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14 July 2018

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Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition

14 July 2018

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Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

14 July 2018

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Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

14 July 2018

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Molecular and cellular basis for anti-amyloid therapy in Alzheimer disease

14 July 2018

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BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time

14 July 2018

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Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

14 July 2018

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Alzheimer Disease in the US Population

14 July 2018

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14 July 2018

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Alzheimer disease therapy: can the amyloid cascade be halted?

14 July 2018

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

14 July 2018

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14 July 2018

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The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances

14 July 2018

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Cholinesterase inhibitor treatment alters the natural history of Alzheimer's disease

14 July 2018

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Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development

14 July 2018

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

14 July 2018

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

14 July 2018

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Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

14 July 2018

1 reference

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

14 July 2018

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

14 July 2018

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Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

14 July 2018

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Cross-national comparisons of the occurrence of Alzheimer's and vascular dementias

14 July 2018

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Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.

14 July 2018

1 reference

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Safety, tolerability, and changes in amyloid beta concentrations after administration of a gamma-secretase inhibitor in volunteers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894844

Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894844

Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894844

Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor

31 October 2018

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Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation

31 October 2018

1 reference

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Immunotherapy for Alzheimer's disease

31 October 2018

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Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

31 October 2018

1 reference

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Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial

31 October 2018

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Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

31 October 2018

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Randomized, Placebo-Controlled Trial of the Effects of Donepezil on Neuronal Markers and Hippocampal Volumes in Alzheimer’s Disease

31 October 2018

1 reference

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Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial

31 October 2018

1 reference

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31 October 2018

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Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease

31 October 2018

1 reference

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Memantine in moderate-to-severe Alzheimer's disease

31 October 2018

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31 October 2018

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Glycosaminoglycan mimetics: a therapeutic approach to cerebral amyloid angiopathy

31 October 2018

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

31 October 2018

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The effects of a novel NSAID on chronic neuroinflammation are age dependent.

31 October 2018

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A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.

31 October 2018

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Alzheimer's disease care: costs and potential savings

31 October 2018

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Clinical trial of indomethacin in Alzheimer's disease.

31 October 2018

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Apolipoprotein E polymorphism and Alzheimer's disease.

31 October 2018

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Evaluation of the safety and immunogenicity of synthetic A 42 (AN1792) in patients with AD

31 October 2018

1 reference

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Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

31 October 2018

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Explaining the cause of the amyloid burden in Alzheimer disease

31 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/17599166

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/17599166

12 December 2020

inferred from PubMed ID database lookup

Transgenic AD model mice, effects of potential anti-AD treatments on inflammation and pathology

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PubMed

https://pubmed.ncbi.nlm.nih.gov/17599166

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4088/PCC.V09N0106

1 reference

release_yzfu47bpgjddjngz7ykwyvtidq

25 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yzfu47bpgjddjngz7ykwyvtidq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1894844

1 reference

25 July 2017

1 reference