Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity (Q33322892)

25 July 2017

title

Negative feedback regulation of T cells via interleukin-2 and FOXP3 reciprocity (English)

1 reference

25 July 2017

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2

Kendall A Smith

1 reference

25 July 2017

Zoran Popmihajlov

1

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25 July 2017

language of work or name

English

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publication date

13 February 2008

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25 July 2017

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25 July 2017

volume

3

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25 July 2017

issue

2

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25 July 2017

page(s)

e1581

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Creative Commons Attribution 4.0 International

25 July 2017

copyright license

start time

13 February 2008

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

21 June 2018

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21 June 2018

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

21 June 2018

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Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression

21 June 2018

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IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells

21 June 2018

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

21 June 2018

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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

21 June 2018

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

21 June 2018

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Foxp3 occupancy and regulation of key target genes during T-cell stimulation

21 June 2018

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21 June 2018

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Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.

21 June 2018

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Nonredundant roles for Stat5a/b in directly regulating Foxp3

21 June 2018

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FOXP3: not just for regulatory T cells anymore

21 June 2018

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FOXP3 controls regulatory T cell function through cooperation with NFAT

21 June 2018

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Foxp3 represses retroviral transcription by targeting both NF-kappaB and CREB pathways

21 June 2018

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IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

21 June 2018

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

21 June 2018

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EXCEPTIONAL INHERITANCE OF A SEX-LINKED GENE IN THE MOUSE EXPLAINED ON THE BASIS THAT THE X/O SEX-CHROMOSOME CONSTITUTION IS FEMALE

21 June 2018

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Molecular mechanisms underlying FOXP3 induction in human T cells

21 June 2018

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Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

21 June 2018

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In vivo instruction of suppressor commitment in naive T cells

21 June 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 June 2018

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

21 June 2018

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Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma

21 June 2018

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 June 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 June 2018

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Control of regulatory T cell development by the transcription factor Foxp3

21 June 2018

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The amount of scurfin protein determines peripheral T cell number and responsiveness

21 June 2018

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Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation

21 June 2018

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 June 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 June 2018

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 June 2018

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JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

21 June 2018

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Cellular and molecular characterization of the scurfy mouse mutant

21 June 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 June 2018

1 reference

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CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance

21 June 2018

1 reference

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A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

CD4+CD8- T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Generalized autoimmune disease in interleukin-2-deficient mice is triggered by an uncontrolled activation and proliferation of CD4+ T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Interleukin-2: inception, impact, and implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

The interleukin 2 receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

T cell growth factor: parameters of production and a quantitative microassay for activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265256

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001581

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001581

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001581

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001581

Inducing and expanding regulatory T cell populations by foreign antigen

21 January 2018

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12 December 2020

Interleukin-2 is indispensable for development of immunological self-tolerance

1 reference

12 December 2020

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

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12 December 2020

Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen

1 reference

12 December 2020

Pathogenesis of post-thymectomy autoimmune gastritis. Identification of anti-H/K adenosine triphosphatase-reactive T cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0001581

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DOI

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25 July 2017

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25 July 2017

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