Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania major (Q33350046)

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30 August 2019

title

Gene disruption of the DNA topoisomerase IB small subunit induces a non-viable phenotype in the hemoflagellate Leishmania major (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18611247%20AND%20SRC:MED&resulttype=core&format=json

DNA topoisomerase type IB small subunit, putative

30 August 2019

main subject

1 reference

GeneDB

DNA topoisomerase IB, large subunit

5 February 2019

1 reference

GeneDB

DNA topoisomerase type IB small subunit, putative

6 February 2019

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DNA topoisomerase IB, large subunit

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DNA topoisomerase type IB small subunit, putative

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DNA topoisomerase IB, large subunit

0 references

Leishmania major

object named as

Leishmania major

1 reference

1 reference

1

1 reference

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30 August 2019

Carlos Garcia-Estrada

2

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30 August 2019

Yolanda Pérez-Pertejo

3

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30 August 2019

Rosa M. Reguera

4

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30 August 2019

author name string

Rafael Balaña-Fouce

1

1 reference

26 July 2017

8 July 2008

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30 August 2019

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30 August 2019

volume

8

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30 August 2019

page(s)

113

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https://scigraph.springernature.com/pub.10.1186/1471-2180-8-113

30 August 2019

exact match

0 references

cites work

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Camptothecins and Topoisomerase I; A Foot in the Door. Targeting the Genome Beyond Topoisomerase I with Camptothecins and Novel Anticancer Drugs; Importance of DNA Replication, Repair and Cell Cycle Checkpoints

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14 July 2018

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A novel active DNA topoisomerase I in Leishmania donovani.

14 July 2018

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Cellular roles of dna topoisomerases: a molecular perspective

14 July 2018

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RNA interference of a trypanosome topoisomerase II causes progressive loss of mitochondrial DNA.

14 July 2018

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Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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RNA interference of Trypanosoma brucei topoisomerase IB: both subunits are essential

31 October 2018

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Camptothecin-induced imbalance in intracellular cation homeostasis regulates programmed cell death in unicellular hemoflagellate Leishmania donovani

31 October 2018

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Camptothecin induced mitochondrial dysfunction leading to programmed cell death in unicellular hemoflagellate Leishmania donovani

31 October 2018

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Programmed cell death in the unicellular protozoan parasite Leishmania

31 October 2018

1 reference

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Nucleolar delocalization of human topoisomerase I in response to topotecan correlates with sumoylation of the protein

31 October 2018

1 reference

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Histone synthesis in Leishmania infantum is tightly linked to DNA replication by a translational control

31 October 2018

1 reference

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Protein kinase C phosphorylates DNA topoisomerase I

31 October 2018

1 reference

12 December 2020

Two more independent selectable markers for stable transfection of Leishmania

1 reference

12 December 2020

Use of the green fluorescent protein as a marker in transfected Leishmania

1 reference

12 December 2020

Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I

1 reference

12 December 2020

Cutaneous leishmaniasis

1 reference

12 December 2020

Cutaneous leishmaniasis

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2180-8-113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18611247%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 August 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18611247%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

1 reference