The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53 (Q33350162)

26 July 2017

title

The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53 (English)

1 reference

26 July 2017

2

Sandra Blanco

1 reference

26 July 2017

Francisco M Vega

3

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Pedro A. Lazo

object named as

Pedro A Lazo

series ordinal

4

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author name string

Alberto Valbuena

series ordinal

1

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26 July 2017

language of work or name

English

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publication date

9 July 2008

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26 July 2017

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26 July 2017

volume

3

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26 July 2017

issue

7

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26 July 2017

page(s)

e2649

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Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

9 July 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Alteration of the VRK1-p53 autoregulatory loop in human lung carcinomas

21 June 2018

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Site-specific acetylation of p53 directs selective transcription complex assembly.

21 June 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 June 2018

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PCAF modulates PTEN activity

21 June 2018

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p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop

21 June 2018

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The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines

21 June 2018

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The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway

21 June 2018

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Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53

21 June 2018

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VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

21 June 2018

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p53 isoforms can regulate p53 transcriptional activity.

21 June 2018

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p53 Stabilization and accumulation induced by human vaccinia-related kinase 1

21 June 2018

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Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

21 June 2018

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CBP and p300: HATs for different occasions

21 June 2018

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The p53 response to DNA damage

21 June 2018

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Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

21 June 2018

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The MDM2-p53 interaction.

21 June 2018

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p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

21 June 2018

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Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5

21 June 2018

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Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 June 2018

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The protein kinase complement of the human genome

21 June 2018

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p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro

21 June 2018

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Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p300 Modulates the BRCA1 inhibition of estrogen receptor activity

21 June 2018

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Functional interaction between coactivators CBP/p300, PCAF, and transcription factor FKLF2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p300/CBP/p53 interaction and regulation of the p53 response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Regulation of p53 function and stability by phosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Identification of two novel human putative serine/threonine kinases, VRK1 and VRK2, with structural similarity to vaccinia virus B1R kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Recruitment of p300/CBP in p53-dependent signal pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

CBP-induced stimulation of c-Fos activity is abrogated by E1A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002649

Mdm-2 binding and TAF(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues Thr18 and Asp21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002649

Conjunction dysfunction: CBP/p300 in human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002649

p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0002649

Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441436

p53 transactivation domain mutant Q22, S23 is impaired for repression of promoters and mediation of apoptosis

31 October 2018

1 reference

12 December 2020

Role for p300 in stabilization of p53 in the response to DNA damage

1 reference

12 December 2020

Expression of a new isoform of the tumor susceptibility TSG101 protein lacking a leucine zipper domain in Burkitt lymphoma cell lines

1 reference

12 December 2020

Function for p300 and not CBP in the apoptotic response to DNA damage

1 reference

12 December 2020

p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation

1 reference

12 December 2020

CREB-binding protein/p300 activates MyoD by acetylation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0002649

Identifiers

DOI

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26 July 2017

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26 July 2017

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