Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells (Q33403191)

26 July 2017

title

Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells (English)

1 reference

26 July 2017

Kian Leong Lee

2

0 references

author name string

Marcela Guzman-Ayala

1

1 reference

26 July 2017

Konstantinos J Mavrakis

3

1 reference

26 July 2017

Paraskevi Goggolidou

4

1 reference

26 July 2017

Dominic P Norris

5

1 reference

26 July 2017

Vasso Episkopou

6

1 reference

26 July 2017

language of work or name

English

0 references

publication date

27 January 2009

1 reference

26 July 2017

1 reference

26 July 2017

volume

4

1 reference

26 July 2017

issue

1

1 reference

26 July 2017

page(s)

e4268

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

27 January 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

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Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.

21 June 2018

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A gene network establishing polarity in the early mouse embryo

21 June 2018

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Gastrula organiser and embryonic patterning in the mouse

21 June 2018

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21 June 2018

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New insights into TGF-beta-Smad signalling

21 June 2018

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Development of definitive endoderm from embryonic stem cells in culture

21 June 2018

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Morphogens, their identification and regulation

21 June 2018

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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells

21 June 2018

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Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 June 2018

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Nodal Signaling in Vertebrate Development

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo

21 June 2018

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21 June 2018

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21 June 2018

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Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

From fertilization to gastrulation: axis formation in the mouse embryo.

21 June 2018

1 reference

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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Role of the anterior visceral endoderm in restricting posterior signals in the mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

The EGF-CFC gene family in vertebrate development.

21 June 2018

1 reference

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21 June 2018

1 reference

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Smads as transcriptional co-modulators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Establishment in culture of pluripotential cells from mouse embryos

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2627943

The EGF-CFC protein one-eyed pinhead is essential for nodal signaling

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19172185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of nodal signaling targets by array analysis of induced complex probes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19172185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19172185

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0004268

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference