Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity (Q33572896)

28 July 2017

title

Minimal-length short hairpin RNAs: the relationship of structure and RNAi activity (English)

1 reference

28 July 2017

Brian H Johnston

7

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author name string

Qing Ge

1

1 reference

28 July 2017

Heini Ilves

2

1 reference

28 July 2017

Anne Dallas

3

1 reference

28 July 2017

Pavan Kumar

4

1 reference

28 July 2017

Joshua Shorenstein

5

1 reference

28 July 2017

Sergei A Kazakov

6

1 reference

28 July 2017

language of work or name

English

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publication date

1 December 2009

1 reference

28 July 2017

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28 July 2017

volume

16

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28 July 2017

issue

1

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28 July 2017

page(s)

106-117

1 reference

Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs

28 July 2017

cites work

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21 June 2018

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Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Conversion of stable RNA hairpin to a metastable dimer in frozen solution

21 June 2018

1 reference

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Defining the optimal parameters for hairpin-based knockdown constructs

21 June 2018

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shRNAs targeting hepatitis C: effects of sequence and structural features, and comparision with siRNA.

21 June 2018

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Rational design and in vitro and in vivo delivery of Dicer substrate siRNA.

21 June 2018

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Illuminating the silence: understanding the structure and function of small RNAs

21 June 2018

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RNA interference from multimeric shRNAs generated by rolling circle transcription

21 June 2018

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Vector-based RNAi approaches for stable, inducible and genome-wide screens

21 June 2018

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Lessons from Nature: microRNA-based shRNA libraries

21 June 2018

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shRNA libraries and their use in cancer genetics

21 June 2018

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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 June 2018

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A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

21 June 2018

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21 June 2018

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Second-generation shRNA libraries covering the mouse and human genomes

21 June 2018

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A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 June 2018

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Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo

21 June 2018

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Single-molecule FRET studies of important intermediates in the nucleocapsid-protein-chaperoned minus-strand transfer step in HIV-1 reverse transcription

21 June 2018

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

21 June 2018

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Functional polarity is introduced by Dicer processing of short substrate RNAs

21 June 2018

1 reference

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Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model

21 June 2018

1 reference

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RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

21 June 2018

1 reference

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 June 2018

1 reference

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siRNAs: applications in functional genomics and potential as therapeutics

21 June 2018

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Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 June 2018

1 reference

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 June 2018

1 reference

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Asymmetry in the assembly of the RNAi enzyme complex

21 June 2018

1 reference

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Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

21 June 2018

1 reference

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Expression profiling reveals off-target gene regulation by RNAi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

siRNAs can function as miRNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

siRNA-mediated gene silencing in vitro and in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Gene silencing using micro-RNA designed hairpins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

ATP requirements and small interfering RNA structure in the RNA interference pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Synthetic shRNAs as potent RNAi triggers.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802021

Inhibition of Hepatitis C IRES-Mediated Gene Expression by Small Hairpin RNAs in Human Hepatocytes and Mice

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19952116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of hairpin-duplex conversion for the HIV-1 dimerization initiation site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19952116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.1894510

1 reference

28 July 2017

1 reference

28 July 2017

1 reference