USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses (Q33655162)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

title

USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1

1 reference

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16 March 2020

Stephanie S. Watowich

13

1 reference

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16 March 2020

author name string

Jin Jin

2

1 reference

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16 March 2020

Hongbo Hu

3

1 reference

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16 March 2020

Haiyan S Li

4

1 reference

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16 March 2020

Simona Romano

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Yichuan Xiao

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Mako Nakaya

7

1 reference

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16 March 2020

Xiaofei Zhou

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Xuhong Cheng

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Peirong Yang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Guillermina Lozano

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Chengming Zhu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Stephen E Ullrich

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

Shao-Cong Sun

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

language of work or name

English

0 references

publication date

28 April 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

volume

15

1 reference

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16 March 2020

issue

6

1 reference

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16 March 2020

page(s)

562-570

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

MDM2, MDMX and p53 in oncogenesis and cancer therapy

16 March 2020

cites work

1 reference

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Molecular pathways: targeting Mdm2 and Mdm4 in cancer therapy

21 June 2018

1 reference

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Th9 cells promote antitumor immune responses in vivo

21 June 2018

1 reference

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Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

21 June 2018

1 reference

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Combining immunotherapy and targeted therapies in cancer treatment

21 June 2018

1 reference

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Regulation of NF-κB by deubiquitinases

21 June 2018

1 reference

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USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

21 June 2018

1 reference

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Deubiquitinases in cancer: new functions and therapeutic options.

21 June 2018

1 reference

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USP15 is a deubiquitylating enzyme for receptor-activated SMADs

21 June 2018

1 reference

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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

21 June 2018

1 reference

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RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

21 June 2018

1 reference

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Structure of the USP15 N-terminal domains: a β-hairpin mediates close association between the DUSP and UBL domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53.

21 June 2018

1 reference

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Inactivation of HAUSP in vivo modulates p53 function

21 June 2018

1 reference

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Breaking the chains: structure and function of the deubiquitinases

21 June 2018

1 reference

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The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability

21 June 2018

1 reference

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

21 June 2018

1 reference

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The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Nonproteolytic functions of ubiquitin in cell signaling

21 June 2018

1 reference

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21 June 2018

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Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 June 2018

1 reference

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Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2.

21 June 2018

1 reference

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Deubiquitylation and regulation of the immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

B16 as a mouse model for human melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Multiple roles for CD4+ T cells in anti-tumor immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

21 June 2018

1 reference

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Immunity by ubiquitylation: a reversible process of modification

21 June 2018

1 reference

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Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT

21 June 2018

1 reference

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The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1

21 June 2018

1 reference

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NFAT proteins: key regulators of T-cell development and function

21 June 2018

1 reference

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Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth.

21 June 2018

1 reference

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Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

21 June 2018

1 reference

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 June 2018

1 reference

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Study of T-cell signaling by somatic cell mutagenesis and complementation cloning

21 June 2018

1 reference

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Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Regulation of interferon-gamma gene expression by nuclear factor of activated T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Identification, functional characterization, and chromosomal localization of USP15, a novel human ubiquitin-specific protease related to the UNP oncoprotein, and a systematic nomenclature for human ubiquitin-specific proteases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

21 June 2018

1 reference

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DNA-dependent protein kinase inhibitor (OK-1035) suppresses p21 expression in HCT116 cells containing wild-type p53 induced by adriamycin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4032322

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.2885

Cutting edge: CD4 and CD8 T cells are intrinsically different in their proliferative responses

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24777531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24777531

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2885

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

release_je3iwok6wfdg3hwlje4pftq2eu

16 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/je3iwok6wfdg3hwlje4pftq2eu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

PubMed publication ID

24777531

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24777531%20AND%20SRC:MED&resulttype=core&format=json