Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. (Q33661151)

28 July 2017

title

Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. (English)

1 reference

28 July 2017

Yaroslava Ruzankina

1

1 reference

28 July 2017

David W Schoppy

2

1 reference

28 July 2017

Amma Asare

3

1 reference

28 July 2017

Carolyn E Clark

4

1 reference

28 July 2017

Robert H Vonderheide

5

1 reference

28 July 2017

Eric J Brown

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

30 August 2009

1 reference

28 July 2017

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28 July 2017

volume

41

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28 July 2017

issue

10

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28 July 2017

page(s)

1144-1149

1 reference

A two-step mechanism for stem cell activation during hair regeneration

28 July 2017

cites work

1 reference

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21 June 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 June 2018

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Senescence of activated stellate cells limits liver fibrosis

21 June 2018

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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

21 June 2018

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21 June 2018

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The ATR pathway: fine-tuning the fork

21 June 2018

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Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development

21 June 2018

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Increased p53 activity does not accelerate telomere-driven ageing

21 June 2018

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Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

21 June 2018

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Capturing and profiling adult hair follicle stem cells.

21 June 2018

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Targeting the checkpoint kinases: chemosensitization versus chemoprotection

21 June 2018

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Modulation of mammalian life span by the short isoform of p53.

21 June 2018

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Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

21 June 2018

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Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

21 June 2018

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21 June 2018

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ATR and ATRIP: partners in checkpoint signaling

21 June 2018

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ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

21 June 2018

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DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

21 June 2018

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Analysis of ku80-mutant mice and cells with deficient levels of p53

21 June 2018

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 June 2018

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ATR disruption leads to chromosomal fragmentation and early embryonic lethality

21 June 2018

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 June 2018

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Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice

21 June 2018

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Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 June 2018

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A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 June 2018

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ATR and H2AX cooperate in maintaining genome stability under replication stress

21 June 2018

1 reference

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Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

30 October 2018

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p53 is essential for chemotherapy-induced hair loss

30 October 2018

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30 October 2018

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Delayed ageing through damage protection by the Arf/p53 pathway

30 October 2018

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ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

30 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19718024

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.441

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.441

1 reference

28 July 2017

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28 July 2017

1 reference