Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae. (Q33681974)

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13 February 2020

title

Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae (English)

1 reference

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Replication factor A subunit protein RFA1 YAR007C

13 February 2020

main subject

1 reference

Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2 YHR164C

1 reference

ATP-dependent DNA helicase SGS1 YMR190C

1 reference

MRX complex nuclease subunit YMR224C

1 reference

DNA topoisomerase 3 YLR234W

1 reference

MRX complex DNA-binding subunit YNL250W

1 reference

Rfa3p YJL173C

1 reference

Xrs2p YDR369C

1 reference

Rmi1p YPL024W

1 reference

Rfa2p YNL312W

1 reference

Saccharomyces cerevisiae

1 reference

5

1 reference

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13 February 2020

Hung-Yuan Chi

6

1 reference

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13 February 2020

author name string

Hengyao Niu

1

1 reference

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13 February 2020

Woo-Hyun Chung

2

1 reference

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13 February 2020

Zhu Zhu

3

1 reference

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13 February 2020

Youngho Kwon

4

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13 February 2020

Rohit Prakash

7

1 reference

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13 February 2020

Changhyun Seong

8

1 reference

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13 February 2020

Dongqing Liu

9

1 reference

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13 February 2020

Lucy Lu

10

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13 February 2020

Grzegorz Ira

11

1 reference

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13 February 2020

Patrick Sung

12

1 reference

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13 February 2020

language of work or name

English

0 references

publication date

1 September 2010

1 reference

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13 February 2020

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13 February 2020

volume

467

1 reference

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issue

7311

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13 February 2020

page(s)

108-111

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https://scigraph.springernature.com/pub.10.1038/nature09318

13 February 2020

exact match

0 references

cites work

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.

1 reference

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Multiplicity of DNA end resection machineries in chromosome break repair

21 June 2018

1 reference

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Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

21 June 2018

1 reference

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Nucleases and helicases take center stage in homologous recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

21 June 2018

1 reference

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Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Processing of G4 DNA by Dna2 helicase/nuclease and replication protein A (RPA) provides insights into the mechanism of Dna2/RPA substrate recognition

21 June 2018

1 reference

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Binding and activation of DNA topoisomerase III by the Rmi1 subunit

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Mechanism of homologous recombination: mediators and helicases take on regulatory functions

21 June 2018

1 reference

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Recombination proteins in yeast

21 June 2018

1 reference

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Flap endonuclease 1: a central component of DNA metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

The Bloom's syndrome helicase suppresses crossing over during homologous recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA Ends

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Bimodal interaction between replication-protein A and Dna2 is critical for Dna2 function both in vivo and in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

21 June 2018

1 reference

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Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

21 June 2018

1 reference

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Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

21 June 2018

1 reference

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Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11.

21 June 2018

1 reference

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The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2955862

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae

21 June 2018

1 reference

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DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes

21 June 2018

1 reference

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Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation

21 June 2018

1 reference

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Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20811460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Human homologues of yeast helicase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20811460

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE09318

1 reference

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Dimensions Publication ID

13 February 2020

0 references

1 reference

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13 February 2020

1 reference