Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan (Q33694302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20195385%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan (English)

1 reference

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19 January 2020

0 references

1 reference

1 reference

6

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19 January 2020

8

Stephen L Helfand

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19 January 2020

author name string

Yih-Woei C Fridell

1

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19 January 2020

Melissa Hoh

2

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19 January 2020

Orsolya Kréneisz

3

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19 January 2020

Suzanne Hosier

4

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19 January 2020

Chengyi Chang

5

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19 January 2020

Daniel K Mulkey

7

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19 January 2020

publication date

21 July 2009

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19 January 2020

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19 January 2020

volume

1

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19 January 2020

page(s)

699-713

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19 January 2020

issue

8

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On the role of uncoupling protein-2 in pancreatic beta cells.

19 January 2020

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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

21 June 2018

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Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

21 June 2018

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21 June 2018

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Molecular defects in insulin secretion in type-2 diabetes

21 June 2018

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Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

21 June 2018

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Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

21 June 2018

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The endocrine regulation of aging by insulin-like signals

21 June 2018

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21 June 2018

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 June 2018

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Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

21 June 2018

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The role of phosphoinositide 3-kinase lipid products in cell function

21 June 2018

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21 June 2018

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21 June 2018

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Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.

21 June 2018

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Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary.

30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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30 October 2018

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Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion

30 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20195385

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/AGING.100067

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20195385%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20195385%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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