In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics (Q33694597)

28 July 2017

In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics (English)

1 reference

28 July 2017

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3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Brooke Bullock Lao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Ivan Grishagin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Thomas F Brewer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Bogdan Z Olenyuk

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Paramjit S Arora

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

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publication date

12 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

111

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3 June 2020

page(s)

7531-7536

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3 June 2020

issue

21

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describes a project that uses

3 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4040591/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

α-Helix mimetics: outwards and upwards

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Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling.

21 June 2018

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A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.

21 June 2018

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Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer

21 June 2018

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Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.

21 June 2018

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Allosteric inhibition of hypoxia inducible factor-2 with small molecules

21 June 2018

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Inhibition of α-helix-mediated protein-protein interactions using designed molecules

21 June 2018

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Plucking the high hanging fruit: a systematic approach for targeting protein-protein interactions

21 June 2018

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Fine-tuning multiprotein complexes using small molecules

21 June 2018

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Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

21 June 2018

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Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors

21 June 2018

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Assessing helical protein interfaces for inhibitor design

21 June 2018

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Minimalist and universal peptidomimetics.

21 June 2018

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Hallmarks of Cancer: The Next Generation

21 June 2018

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Transient protein-protein interactions: structural, functional, and network properties

21 June 2018

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Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitors

21 June 2018

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21 June 2018

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Disrupting protein-protein interactions with non-peptidic, small molecule alpha-helix mimetics

21 June 2018

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A complex task? Direct modulation of transcription factors with small molecules

21 June 2018

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Transcriptional switches: chemical approaches to gene regulation

21 June 2018

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Inhibition of hypoxia inducible factor 1-transcription coactivator interaction by a hydrogen bond surrogate alpha-helix

21 June 2018

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Direct inhibition of hypoxia-inducible transcription factor complex with designed dimeric epidithiodiketopiperazine

21 June 2018

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An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia.

21 June 2018

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Design, synthesis, and evaluation of an alpha-helix mimetic library targeting protein-protein interactions

21 June 2018

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

21 June 2018

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Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

21 June 2018

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Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface

21 June 2018

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Confluence-dependent resistance to doxorubicin in human MDA-MB-231 breast carcinoma cells requires hypoxia-inducible factor-1 activity

21 June 2018

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Regulation of angiogenesis by hypoxia-inducible factor 1.

21 June 2018

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CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding

21 June 2018

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Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist

21 June 2018

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Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

21 June 2018

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Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

21 June 2018

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Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

21 June 2018

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CREB-binding protein and p300 in transcriptional regulation

21 June 2018

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21 June 2018

The Hallmarks of Cancer

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Anatomy of hot spots in protein interfaces

21 June 2018

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040591

A hot spot of binding energy in a hormone-receptor interface

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040591

Atomic interactions and profile of small molecules disrupting protein-protein interfaces: the TIMBAL database.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402393111

Computational alanine scanning of protein-protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402393111

Three conformational states of the p300 CH1 domain define its functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402393111

Enhancement of gene expression under hypoxic conditions using fragments of the human vascular endothelial growth factor and the erythropoietin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1402393111

Oligooxopiperazines as nonpeptidic alpha-helix mimetics

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24821806

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1402393111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24821806%20AND%20SRC:MED&resulttype=core&format=json