Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis (Q33752236)

29 July 2017

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis (English)

1 reference

29 July 2017

1 reference

Joana Gigante

3

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Marina Badenes

object named as

Marina Badenes

4

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Alexandre Trindade

object named as

Alexandre Trindade

2

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author name string

Dusan Djokovic

1

1 reference

29 July 2017

Lilliana Silva

5

1 reference

29 July 2017

Ren Liu

6

1 reference

29 July 2017

Xiuqing Li

7

1 reference

29 July 2017

Ming Gong

8

1 reference

29 July 2017

Valery Krasnoperov

9

1 reference

29 July 2017

Parkash S Gill

10

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29 July 2017

Antonio Duarte

11

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29 July 2017

language of work or name

English

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publication date

23 November 2010

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29 July 2017

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29 July 2017

10

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29 July 2017

641

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3001720/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2407-10-641

0 references

cites work

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KSHV-induced notch components render endothelial and mural cell characteristics and cell survival

21 June 2018

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RGS5, a hypoxia-inducible apoptotic stimulator in endothelial cells

21 June 2018

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Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

21 June 2018

1 reference

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NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1

21 June 2018

1 reference

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21 June 2018

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The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade

21 June 2018

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Modes of resistance to anti-angiogenic therapy

21 June 2018

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Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion

21 June 2018

1 reference

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The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

21 June 2018

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Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

21 June 2018

1 reference

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Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

21 June 2018

1 reference

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Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

21 June 2018

1 reference

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The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth

21 June 2018

1 reference

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Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function

21 June 2018

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Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function

21 June 2018

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Endothelial/pericyte interactions

21 June 2018

1 reference

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Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

21 June 2018

1 reference

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Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

21 June 2018

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Dosage-sensitive requirement for mouse Dll4 in artery development

21 June 2018

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The gamma-secretase complex: machinery for intramembrane proteolysis

21 June 2018

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Functional significance of Tie2 signaling in the adult vasculature

21 June 2018

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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

21 June 2018

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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 June 2018

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

21 June 2018

1 reference

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Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

21 June 2018

1 reference

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Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

21 June 2018

1 reference

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Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

21 June 2018

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Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

21 June 2018

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Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

21 June 2018

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Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-641

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-641

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-641

Cardiovascular ephrinB2 function is essential for embryonic angiogenesis.

21 January 2018

1 reference

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Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms

30 October 2018

1 reference

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Chronic DLL4 blockade induces vascular neoplasms

30 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-641

Vascular normalization in Rgs5-deficient tumours promotes immune destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-10-641

Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21092311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21092311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-10-641

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference