Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema (Q33757076)

29 July 2017

Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema (English)

1 reference

29 July 2017

1 reference

Khalil J Diab

1

1 reference

29 July 2017

Jeremy J Adamowicz

2

1 reference

29 July 2017

Krzysztof Kamocki

3

1 reference

29 July 2017

Natalia I Rush

4

1 reference

29 July 2017

Jana Garrison

5

1 reference

29 July 2017

Yuan Gu

6

1 reference

29 July 2017

Kelly S Schweitzer

7

1 reference

29 July 2017

Anastasia Skobeleva

8

1 reference

29 July 2017

Gangaraju Rajashekhar

9

1 reference

29 July 2017

Walter C Hubbard

10

1 reference

29 July 2017

Evgeny V Berdyshev

11

1 reference

29 July 2017

Irina Petrache

12

1 reference

29 July 2017

language of work or name

English

0 references

publication date

3 December 2009

1 reference

American Journal of Respiratory and Critical Care Medicine

29 July 2017

1 reference

29 July 2017

181

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29 July 2017

4

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29 July 2017

344-352

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Ceramide synthesis is modulated by the sphingosine analog FTY720 via a mixture of uncompetitive and noncompetitive inhibition in an Acyl-CoA chain length-dependent manner

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Lysophospholipid receptors in vertebrate development, physiology, and pathology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Apoptotic sphingolipid signaling by ceramides in lung endothelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

21 June 2018

Caspase activity assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

A novel antiapoptotic role for alpha1-antitrypsin in the prevention of pulmonary emphysema

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Products by the sphingosine kinase/sphingosine 1-phosphate (S1P) lyase pathway but not S1P stimulate mitogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Alveolar wall apoptosis causes lung destruction and emphysematous changes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Sphingosine-1-phosphate: dual messenger functions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

The Edg family G protein-coupled receptors for lysophospholipids: their signaling properties and biological activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Sphingosine 1-phosphate, a key cell signaling molecule

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Vascular atrophy and VEGFR-2 signaling: old theories of pulmonary emphysema meet new data

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Sphingolipid regulation of female gonadal cell apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

Apoptosis and emphysema: the missing link.

21 June 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

S1P(1)-selective agonist, SEW2871, ameliorates ischemic acute renal failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Sphingosine kinase activation mediates ischemic preconditioning in murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Physiologically based pharmacokinetic modeling of FTY720 (2-amino-2[2-(-4-octylphenyl)ethyl]propane-1,3-diol hydrochloride) in rats after oral and intravenous doses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Sphingosine-1-phosphate and its analogue FTY720 diminish acute pulmonary injury in rats with acute necrotizing pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.200906-0826OC

Sphingosine kinase 1 (SK1) is recruited to nascent phagosomes in human macrophages: inhibition of SK1 translocation by Mycobacterium tuberculosis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455841

The definition of emphysema. Report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases workshop

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19965812

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ceramide synthase inhibition by fumonisin B1 treatment activates sphingolipid-metabolizing systems in mouse liver

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19965812

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19965812

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1164/RCCM.200906-0826OC

1 reference

29 July 2017

1 reference

29 July 2017

1 reference