Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer (Q33839938)

29 July 2017

title

Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer (English)

1 reference

29 July 2017

Shane Harding

6

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Daniel Durocher

object named as

Daniel Durocher

10

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Robert G. Bristow

object named as

Robert Bristow

8

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author name string

Li Li

1

1 reference

29 July 2017

Marie-Jo Halaby

2

1 reference

29 July 2017

Anne Hakem

3

1 reference

29 July 2017

Renato Cardoso

4

1 reference

29 July 2017

Samah El Ghamrasni

5

1 reference

29 July 2017

Norman Chan

7

1 reference

29 July 2017

Otto Sanchez

9

1 reference

29 July 2017

Razqallah Hakem

11

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29 July 2017

language of work or name

English

0 references

publication date

12 April 2010

1 reference

Journal of Experimental Medicine

29 July 2017

published in

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29 July 2017

volume

207

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29 July 2017

issue

5

1 reference

29 July 2017

page(s)

983-997

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2867283/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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RNF168, a new RING finger, MIU-containing protein that modifies chromatin by ubiquitination of histones H2A and H2AX

5 July 2018

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5 July 2018

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Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

5 July 2018

1 reference

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Regulatory ubiquitylation in response to DNA double-strand breaks

5 July 2018

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RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

5 July 2018

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5 July 2018

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Histone ubiquitination associates with BRCA1-dependent DNA damage response

5 July 2018

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Non-homologous end joining in class switch recombination: the beginning of the end

5 July 2018

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53BP1 facilitates long-range DNA end-joining during V(D)J recombination

5 July 2018

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Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

5 July 2018

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Mechanism and regulation of class switch recombination

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

5 July 2018

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V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.

5 July 2018

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DNA damage signalling guards against activated oncogenes and tumour progression

5 July 2018

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Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase

5 July 2018

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

5 July 2018

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RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins

5 July 2018

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RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling

5 July 2018

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IgH class switching and translocations use a robust non-classical end-joining pathway

5 July 2018

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Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies

5 July 2018

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Evolution of the immunoglobulin heavy chain class switch recombination mechanism

5 July 2018

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5 July 2018

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5 July 2018

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MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

5 July 2018

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5 July 2018

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5 July 2018

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53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

5 July 2018

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p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

5 July 2018

1 reference

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Genomic instability in mice lacking histone H2AX

5 July 2018

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5 July 2018

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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

5 July 2018

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5 July 2018

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21 January 2018

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20092437

1 reference

29 July 2017

1 reference

29 July 2017

1 reference