Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes. (Q33853031)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

review article

1 reference

title

Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

2

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9 February 2020

author name string

Gwyndolen C Harburg

series ordinal

1

1 reference

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9 February 2020

publication date

5 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

Journal of Mammary Gland Biology and Neoplasia

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

16

1 reference

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9 February 2020

issue

3

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9 February 2020

page(s)

257-270

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SLIT/ROBO1 signaling suppresses mammary branching morphogenesis by limiting basal cell number

9 February 2020

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells

5 July 2018

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Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells

5 July 2018

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SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium

5 July 2018

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Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor

5 July 2018

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Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells

5 July 2018

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Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.

5 July 2018

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Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells

5 July 2018

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EphrinB1 controls cell-cell junctions through the Par polarity complex

5 July 2018

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The semaphorins: versatile regulators of tumour progression and tumour angiogenesis

5 July 2018

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The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

5 July 2018

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Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer

5 July 2018

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A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells

5 July 2018

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The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

5 July 2018

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ErbB-2 and met reciprocally regulate cellular signaling via plexin-B1.

5 July 2018

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Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding

5 July 2018

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Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins

5 July 2018

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Structural basis for ligand and heparin binding to neuropilin B domains

5 July 2018

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Promoter hypermethylation of p16INK4A, p14ARF, CyclinD2 and Slit2 in serum and tumor DNA from breast cancer patients

5 July 2018

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The neuronal guidance cue Slit2 induces targeted migration and may play a role in brain metastasis of breast cancer cells

5 July 2018

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Characterization of the receptors for axon guidance factor netrin-4 and identification of the binding domains

5 July 2018

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Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis

5 July 2018

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The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

5 July 2018

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Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

5 July 2018

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Semaphorin 4D provides a link between axon guidance processes and tumor-induced angiogenesis.

5 July 2018

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Slit2 and netrin 1 act synergistically as adhesive cues to generate tubular bi-layers during ductal morphogenesis

5 July 2018

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Transcriptional silencing of EphB6 receptor tyrosine kinase in invasive breast carcinoma cells and detection of methylated promoter by methylation specific PCR.

5 July 2018

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Neogenin expression may be inversely correlated to the tumorigenicity of human breast cancer

5 July 2018

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Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

5 July 2018

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A conditional feedback loop regulates Ras activity through EphA2.

5 July 2018

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Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis

5 July 2018

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Involvement of axonal guidance proteins and their signaling partners in the developing mouse mammary gland

5 July 2018

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Semaphorin SEMA3F has a repulsing activity on breast cancer cells and inhibits E-cadherin-mediated cell adhesion

5 July 2018

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The versatile roles of "axon guidance" cues in tissue morphogenesis.

5 July 2018

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5 July 2018

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Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

5 July 2018

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Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect

5 July 2018

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Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

5 July 2018

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Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

5 July 2018

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Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells

5 July 2018

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Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells

5 July 2018

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Semaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreading

5 July 2018

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The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment

5 July 2018

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Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis

5 July 2018

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Molecular mechanisms of axon guidance

5 July 2018

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SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers

5 July 2018

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Identification, characterization, and functional study of the two novel human members of the semaphorin gene family

5 July 2018

1 reference

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Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

5 July 2018

1 reference

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Estrogen and Myc negatively regulate expression of the EphA2 tyrosine kinase

5 July 2018

1 reference

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Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells

5 July 2018

1 reference

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Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

5 July 2018

1 reference

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The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

5 July 2018

1 reference

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Involvement of chemokine receptors in breast cancer metastasis

5 July 2018

1 reference

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Protein kinase expression during murine mammary development

5 July 2018

1 reference

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Homozygous deletions at 3p12 in breast and lung cancer

5 July 2018

1 reference

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Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis

5 July 2018

1 reference

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Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

5 July 2018

1 reference

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Expression of the receptor protein tyrosine kinase myk-1/htk in normal and malignant mammary epithelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

Isolation of the human semaphorin III/F gene (SEMA3F) at chromosome 3p21, a region deleted in lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

Allele loss from 5q21 (APC/MCC) and 18q21 (DCC) and DCC mRNA expression in breast cancer

5 July 2018

1 reference

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Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues

5 July 2018

1 reference

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CXCR4 is expressed in ductal carcinoma in situ of the breast and in atypical ductal hyperplasia

5 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-011-9225-1

Netrin-4 regulates angiogenic responses and tumor cell growth

21 January 2018

1 reference

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Expression of Ephb2 and Ephb4 in breast carcinoma

21 January 2018

1 reference

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The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-011-9225-1

Deregulated ephrin-B2 expression in the mammary gland interferes with the development of both the glandular epithelium and vasculature and promotes metastasis formation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

EphA2 overexpression decreases estrogen dependence and tamoxifen sensitivity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

c-Cbl-dependent EphA2 protein degradation is induced by ligand binding.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4083826

Global search for chromosomal abnormalities in infiltrating ductal carcinoma of the breast using array-comparative genomic hybridization

29 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10911-011-9225-1

Preponderance of cells with stem cell characteristics in metastasising mouse mammary tumours induced by deregulated EphB4 and ephrin-B2 expression

21 January 2018

1 reference

12 December 2020

Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma

1 reference

12 December 2020

Reduced expression of APC and DCC gene protein in breast cancer

1 reference

12 December 2020

E-cadherin regulates the function of the EphA2 receptor tyrosine kinase

1 reference

12 December 2020

Decreased expression of the DCC gene in human breast carcinoma

1 reference

12 December 2020

Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165

1 reference

12 December 2020

Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1

1 reference

12 December 2020

Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis

1 reference

12 December 2020

10.1007/S10911-011-9225-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21818544%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

21818544

1 reference