Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators (Q33876246)

29 July 2017

title

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators (English)

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29 July 2017

14

Peter Wipf

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29 July 2017

Donna M Huryn

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Paul Nghiem

object named as

Paul Nghiem

11

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Kay M. Brummond

3

object named as

Kay M Brummond

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29 July 2017

Jeffrey L Brodsky

2

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29 July 2017

Peter G Chambers

4

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29 July 2017

Benjamin Eyer

5

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29 July 2017

Alex W Ireland

6

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29 July 2017

Masaoki Kawasumi

7

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29 July 2017

Matthew G Laporte

8

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29 July 2017

Kayla Lloyd

9

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29 July 2017

Baptiste Manteau

10

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29 July 2017

Bettina Quade

12

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29 July 2017

Sandlin P Seguin

13

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29 July 2017

language of work or name

English

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publication date

18 April 2011

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

108

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29 July 2017

issue

17

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29 July 2017

page(s)

6757-6762

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The HSP70 chaperone machinery: J proteins as drivers of functional specificity

29 July 2017

cites work

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Binding of a small molecule at a protein-protein interface regulates the chaperone activity of hsp70-hsp40.

5 July 2018

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Current strategies for diversity-oriented synthesis

5 July 2018

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Targeting HSP70: the second potentially druggable heat shock protein and molecular chaperone?

5 July 2018

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5 July 2018

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Heat shock protein 70 (hsp70) as an emerging drug target.

5 July 2018

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Heat stress cognate 70 host protein as a potential drug target against drug resistance in hepatitis B virus

5 July 2018

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Plasmodial heat shock proteins: targets for chemotherapy

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum

5 July 2018

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5 July 2018

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Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation

5 July 2018

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Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins

5 July 2018

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Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer

5 July 2018

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Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulators

5 July 2018

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5 July 2018

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5 July 2018

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Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity.

5 July 2018

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5 July 2018

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Targeting the checkpoint kinases: chemosensitization versus chemoprotection

5 July 2018

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5 July 2018

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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

5 July 2018

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Structural diversity of organic chemistry. A scaffold analysis of the CAS Registry.

5 July 2018

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Crossref

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A precursor-specific role for Hsp40/Hsc70 during tail-anchored protein integration at the endoplasmic reticulum

21 January 2018

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TBAF-catalyzed synthesis of 5-substituted 1H-tetrazoles under solventless conditions.

21 January 2018

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ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

21 January 2018

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12 December 2020

Rhodium(I)-catalyzed ene-allene carbocyclization strategy for the formation of azepines and oxepines

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12 December 2020

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12 December 2020

Microwave-assisted intramolecular [2 + 2] Allenic cycloaddition reaction for the rapid assembly of bicyclo[4.2.0]octa-1,6-dienes and bicyclo[5.2.0]nona-1,7-dienes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1015251108

1 reference

29 July 2017

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29 July 2017

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