Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism (Q33877423)

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English	Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism	scientific article

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8 March 2020

Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism (English)

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8 March 2020

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intellectual disability

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based on heuristic

inferred from title

disability affecting intellectual abilities

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based on heuristic

inferred from title

Simona D'Antoni

1

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8 March 2020

Carmela M Bonaccorso

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8 March 2020

Sebastiano Antonino Musumeci

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8 March 2020

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8 March 2020

Ferdinando Nicoletti

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8 March 2020

Maria Vincenza Catania

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8 March 2020

author name string

Michela Spatuzza

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8 March 2020

Kimberly M Huber

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8 March 2020

publication date

15 February 2014

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8 March 2020

Neuroscience & Biobehavioral Reviews

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8 March 2020

46 Pt 2

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8 March 2020

228-241

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8 March 2020

SHANK3 haploinsufficiency: a "common" but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders

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5 July 2018

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

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Modeling autism by SHANK gene mutations in mice

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Therapeutic approaches for shankopathies

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5 July 2018

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism

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5 July 2018

Epilepsy, autism, and neurodevelopment: kindling a shared vulnerability?

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Spike-driven glutamate electrodiffusion triggers synaptic potentiation via a homer-dependent mGluR-NMDAR link.

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Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

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5 July 2018

Molecular mechanisms coordinating functional and morphological plasticity at the synapse: role of GluA2/N-cadherin interaction-mediated actin signaling in mGluR-dependent LTD.

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PKC phosphorylation regulates mGluR5 trafficking by enhancing binding of Siah-1A.

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Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

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Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome

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Dynamic remodeling of scaffold interactions in dendritic spines controls synaptic excitability.

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Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

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5 July 2018

PTEN signaling in autism spectrum disorders

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5 July 2018

Molecular mechanisms that desensitize metabotropic glutamate receptor signaling: an overview.

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5 July 2018

Preso1 dynamically regulates group I metabotropic glutamate receptors

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5 July 2018

High-throughput sequencing of mGluR signaling pathway genes reveals enrichment of rare variants in autism

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5 July 2018

Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.

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5 July 2018

Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism

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5 July 2018

High proportion of 22q13 deletions and SHANK3 mutations in Chinese patients with intellectual disability

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5 July 2018

SHANK1 Deletions in Males with Autism Spectrum Disorder

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5 July 2018

The pathophysiology of fragile X (and what it teaches us about synapses)

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5 July 2018

Epilepsy and autism: is there a special relationship?

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5 July 2018

Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation

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5 July 2018

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

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5 July 2018

Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex

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5 July 2018

Mutations causing syndromic autism define an axis of synaptic pathophysiology

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Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses

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Rapid synthesis of the X-linked mental retardation protein OPHN1 mediates mGluR-dependent LTD through interaction with the endocytic machinery.

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Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry

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Targeting glutamate synapses in schizophrenia

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5 July 2018

Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism

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5 July 2018

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism

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Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity

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Loss of Tsc1 in vivo impairs hippocampal mGluR-LTD and increases excitatory synaptic function

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Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

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Which comes first in fragile X syndrome, dendritic spine dysgenesis or defects in circuit plasticity?

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Toward fulfilling the promise of molecular medicine in fragile X syndrome

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Metabotropic glutamate receptors: from the workbench to the bedside

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A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.

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Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

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Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome

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Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA.

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Homer1a-dependent crosstalk between NMDA and metabotropic glutamate receptors in mouse neurons

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Mechanism-based approaches to treating fragile X

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5 July 2018

Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease

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Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity

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5 July 2018

Dysregulation of mTOR signaling in fragile X syndrome

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5 July 2018

Metabotropic glutamate receptors: physiology, pharmacology, and disease

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Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

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5 July 2018

Norbin is an endogenous regulator of metabotropic glutamate receptor 5 signaling

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5 July 2018

The slow (<1 Hz) rhythm of non-REM sleep: a dialogue between three cardinal oscillators.

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5 July 2018

Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms.

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5 July 2018

Intracellular metabotropic glutamate receptor 5 (mGluR5) activates signaling cascades distinct from cell surface counterparts

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5 July 2018

Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling

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5 July 2018

Differential distribution of endoplasmic reticulum controls metabotropic signaling and plasticity at hippocampal synapses

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5 July 2018

A synaptic trek to autism

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5 July 2018

Protein translation in synaptic plasticity: mGluR-LTD, Fragile X.

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5 July 2018

Rapid neocortical dynamics: cellular and network mechanisms

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5 July 2018

The postsynaptic density proteins Homer and Shank form a polymeric network structure

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5 July 2018

The state of synapses in fragile X syndrome

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5 July 2018

Cellular plasticity for group I mGluR-mediated epileptogenesis

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5 July 2018

The Autistic Neuron: Troubled Translation?

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5 July 2018

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

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5 July 2018

The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.

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5 July 2018

Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.

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5 July 2018

Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rate

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5 July 2018

Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

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5 July 2018

Deletion 22q13.3 syndrome

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5 July 2018

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

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5 July 2018

Metabotropic glutamate receptors in glial cells.

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5 July 2018

Advances in autism genetics: on the threshold of a new neurobiology

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5 July 2018

Activated nuclear metabotropic glutamate receptor mGlu5 couples to nuclear Gq/11 proteins to generate inositol 1,4,5-trisphosphate-mediated nuclear Ca2+ release

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5 July 2018

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

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5 July 2018

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse

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5 July 2018

Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

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5 July 2018

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

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5 July 2018

Cognitive deficits in Tsc1+/- mice in the absence of cerebral lesions and seizures.

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5 July 2018

Characterization of the role of microtubule-associated protein 1B in metabotropic glutamate receptor-mediated endocytosis of AMPA receptors in hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

The contribution of sleep to hippocampus-dependent memory consolidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Autism-like behavioral phenotypes in BTBR T+tf/J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

The Homer family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Neurexin-neuroligin signaling in synapse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Coordinated memory replay in the visual cortex and hippocampus during sleep

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Boosting slow oscillations during sleep potentiates memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Tetrameric hub structure of postsynaptic scaffolding protein homer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Endocannabinoid-mediated synaptic plasticity in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Pten regulates neuronal arborization and social interaction in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Involvement of IP3 receptors in LTP and LTD induction in guinea pig hippocampal CA1 neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in Fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Allosteric functioning of dimeric class C G-protein-coupled receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Autism and tuberous sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Co-stimulation of mGluR5 and N-Methyl-D-aspartate Receptors Is Required for Potentiation of Excitatory Synaptic Transmission in Hippocampal Neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Activation of Metabotropic Glutamate Receptor mGlu5 on Nuclear Membranes Mediates Intranuclear Ca2+ Changes in Heterologous Cell Types and Neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and Homer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer regulates gain of ryanodine receptor type 1 channel complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Altered synaptic plasticity in a mouse model of fragile X mental retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Receptor activation and homer differentially control the lateral mobility of metabotropic glutamate receptor 5 in the neuronal membrane.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Abnormal development of dendritic spines in FMR1 knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Differential plasma membrane distribution of metabotropic glutamate receptors mGluR1 alpha, mGluR2 and mGluR5, relative to neurotransmitter release sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Homer: a protein that selectively binds metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Desensitization of metabotropic glutamate receptors in neuronal cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

5 July 2018

Targeting the endocannabinoid system in the treatment of fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Transient receptor potential canonical channels regulate the induction of cerebellar long-term depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Inhibitory modulation of cortical up states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Involvement of inositol-1,4,5-trisphosphate receptors in the bidirectional synaptic plasticity induced in hippocampal CA1 neurons by 1-10 Hz low-frequency stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Audiogenic seizure susceptibility is reduced in fragile X knockout mice after introduction of FMR1 transgenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Prolonged epileptiform discharges induced by altered group I metabotropic glutamate receptor-mediated synaptic responses in hippocampal slices of a fragile X mouse model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Characterization of a metabotropic glutamate receptor type 5-green fluorescent protein chimera (mGluR5-GFP): pharmacology, surface expression, and differential effects of Homer-1a and Homer-1c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Competitive interaction of seven in absentia homolog-1A and Ca2+/calmodulin with the cytoplasmic tail of group 1 metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Phosphorylation of mitogen-activated protein kinase in cultured rat cortical glia by stimulation of metabotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Enhanced early developmental expression of the metabotropic glutamate receptor mGluR5 in rat brain: protein, mRNA splice variants, and regional distribution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Glutamate activates phospholipase D in hippocampal slices of newborn and adult rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

The metabotropic glutamate receptors: their second intracellular loop plays a critical role in the G-protein coupling specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Stimulation by glutamate receptors of arachidonic acid release depends on the Na+/Ca2+ exchanger in neuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5499156

29 October 2018

Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/24548786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24548786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical Visualization of the mG1uR1 a Metabotropic Glutamate Receptor at Synapses of Corticothalamic Terminals Originating from Area 17 of the Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24548786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/24548786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homer proteins regulate coupling of group I metabotropic glutamate receptors to N-type calcium and M-type potassium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/24548786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUBIOREV.2014.02.003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24548786%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24548786%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24548786%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

ResearchGate publication ID

0 references

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