Ras activity regulates cyclin E degradation by the Fbw7 pathway. (Q33892360)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15980150%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Ras activity regulates cyclin E degradation by the Fbw7 pathway (English)

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13 January 2020

1

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13 January 2020

Markus Welcker

series ordinal

2

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13 January 2020

author name string

Bruce E Clurman

series ordinal

3

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13 January 2020

language of work or name

English

0 references

publication date

24 June 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15980150%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 January 2020

published in

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13 January 2020

volume

102

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13 January 2020

issue

27

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13 January 2020

page(s)

9649-9654

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15980150%20AND%20SRC:MED&resulttype=core&format=json

Cyclin E in normal and neoplastic cell cycles

13 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

The life cycle of C-myc: from synthesis to degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Normal human fibroblasts are resistant to RAS-induced senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Inactivation of hCDC4 can cause chromosomal instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cyclin E ablation in the mouse

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

The oncogenic activity of cyclin E is not confined to Cdk2 activation alone but relies on several other, distinct functions of the protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Induction of postmitotic neuroretina cell proliferation by distinct Ras downstream signaling pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Deregulated cyclin E induces chromosome instability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cyclin E-CDK2 is a regulator of p27Kip1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172263

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Cyclin E dysregulation and chromosomal instability in endometrial cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Additive effects of tamoxifen and the farnesyl transferase inhibitor FTI-277 on inhibition of MCF-7 breast cancer cell-cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0503677102

Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15980150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ras1 promotes cellular growth in the Drosophila wing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15980150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0503677102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15980150%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15980150%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference