p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation (Q44206924)

30 November 2017

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation (English)

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30 November 2017

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4

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30 November 2017

Jherek Swanger

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30 November 2017

Eileen Bryant

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3

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30 November 2017

Harry Hwang

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5

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30 November 2017

Bruce E Clurman

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6

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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30 November 2017

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21

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30 November 2017

1817-1827

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Principles of CDK regulation

30 November 2017

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Association of human cyclin E with a periodic G1-S phase protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

The RB and p53 pathways in cancer

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Deregulated cyclin E induces chromosome instability

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Cyclin E -- a better prognostic marker for breast cancer than cyclin D?

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Cyclins and breast cancer

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

The DNA damage response: putting checkpoints in perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Cellular senescence: mitotic clock or culture shock?

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2901225-3

7 January 2021

10.1016/S0960-9822(02)01225-3

Identifiers

DOI

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30 November 2017

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