Definition of the p53 functional domains necessary for inducing apoptosis (Q33917509)

30 July 2017

Definition of the p53 functional domains necessary for inducing apoptosis (English)

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30 July 2017

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Zhu J

1

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30 July 2017

Zhang S

series ordinal

2

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30 July 2017

Jiang J

series ordinal

3

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30 July 2017

Chen X

series ordinal

4

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30 July 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

30 July 2017

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30 July 2017

275

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30 July 2017

39927-39934

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30 July 2017

51

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30 July 2017

p53: puzzle and paradigm

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

The p53 family: same response, different signals?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Identification of a novel p53 functional domain that is necessary for mediating apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Definition of a p53 transactivation function-deficient mutant and characterization of two independent p53 transactivation subdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Regulation of the specific DNA binding function of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Small peptides activate the latent sequence-specific DNA binding function of p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Identification of an additional negative regulatory region for p53 sequence-specific DNA binding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Reactivation of mutant p53 through interaction of a C-terminal peptide with the core domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

p53 modulation of TFIIH-associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Physical and functional interaction between p53 and the Werner's syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

p53-mediated apoptosis is attenuated in Werner syndrome cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Essential role for p53-mediated transcription in E1A-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

A model for p53-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Regulation of p53 downstream genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Induction of growth arrest and cell death by overexpression of the cyclin-Cdk inhibitor p21 in hamster BHK21 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Proteolysis by calpains: a possible contribution to degradation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Proteolytic cleavage of human p53 by calpain: a potential regulator of protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Proteolytic cleavage of p53 mutants in response to mismatched DNA.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Regulation of p53 stability by Mdm2

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M005676200

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Regulation of Mdm2-directed degradation by the C terminus of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005676200

21 January 2018

Identifiers

DOI

10.1074/JBC.M005676200

1 reference

30 July 2017

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