Pro-proliferative FoxM1 is a target of p53-mediated repression (Q33966216)

30 July 2017

Pro-proliferative FoxM1 is a target of p53-mediated repression (English)

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30 July 2017

A M Barsotti

1

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30 July 2017

C Prives

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

14 September 2009

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30 July 2017

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30 July 2017

28

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30 July 2017

48

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30 July 2017

4295-4305

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https://scigraph.springernature.com/pub.10.1038/onc.2009.282

30 July 2017

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cites work

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Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression

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Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.

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Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

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Anaphase-promoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase

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FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression.

5 July 2018

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5 July 2018

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The guardian's little helper: microRNAs in the p53 tumor suppressor network

5 July 2018

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Survivin repression by p53, Rb and E2F2 in normal human melanocytes

5 July 2018

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Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells

5 July 2018

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Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process

5 July 2018

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

5 July 2018

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A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment

5 July 2018

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Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes

5 July 2018

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FoxM1: at the crossroads of ageing and cancer

5 July 2018

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Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression

5 July 2018

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The p53 tumor suppressor participates in multiple cell cycle checkpoints

5 July 2018

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p53 and its downstream proteins as molecular targets of cancer

5 July 2018

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FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells

5 July 2018

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The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53.

5 July 2018

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Transcriptional regulation by p53: one protein, many possibilities

5 July 2018

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Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells

5 July 2018

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The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer

5 July 2018

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Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice

5 July 2018

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DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis

5 July 2018

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Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase

5 July 2018

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p53-Dependent transcriptional repression of c-myc is required for G1 cell cycle arrest

5 July 2018

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Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe

5 July 2018

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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

5 July 2018

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The p53 tumor suppressor protein represses human snRNA gene transcription by RNA polymerases II and III independently of sequence-specific DNA binding

5 July 2018

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Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data

5 July 2018

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p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

FoxM1 is required for execution of the mitotic programme and chromosome stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

DNA damage-induced downregulation of Cdc25C is mediated by p53 via two independent mechanisms: one involves direct binding to the cdc25C promoter.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p53-dependent down-regulation of telomerase is mediated by p21waf1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

5 July 2018

MDM2, an introduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Global genechip profiling to identify genes responsive to p53-induced growth arrest and apoptosis in human lung carcinoma cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p21/CDKN1A mediates negative regulation of transcription by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Transcriptional repression mediated by the p53 tumour suppressor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Genomic targets of the human c-Myc protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

FOXM1 is a downstream target of Gli1 in basal cell carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Analyses of p53 target genes in the human genome by bioinformatic and microarray approaches

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

DNA microarrays identification of primary and secondary target genes regulated by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Regulation of the G2/M transition by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p53 down-regulates CHK1 through p21 and the retinoblastoma protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

The tumour suppressor protein p53 can repress transcription of cyclin B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Definition of the p53 functional domains necessary for inducing apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

Participation of p53 protein in the cellular response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells

5 July 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.282

C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Induction of tetraploidy through loss of p53 and upregulation of Plk1 by human papillomavirus type-16 E6.

21 January 2018

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p130/p107/p105Rb-dependent transcriptional repression during DNA-damage-induced cell-cycle exit at G2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Deciphering transcriptional regulatory elements that encode specific cell cycle phasing by comparative genomics analysis.

21 January 2018

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Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway

21 January 2018

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Down-regulation of cyclin A gene expression upon genotoxic stress correlates with reduced binding of free E2F to the promoter

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898139

p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

29 October 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Expression of the cell cycle phosphatase cdc25C is down-regulated by the tumor suppressor protein p53 but not by p73

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.282

Microarray Expression Profiling of p53-Dependent Transcriptional Changes in an Immortalized Mouse Embryo Fibroblast Cell Line

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2009.282

1 reference

Dimensions Publication ID

30 July 2017

0 references

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30 July 2017

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