Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells (Q33971668)

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English	Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells (English)

1 reference

Europe PubMed Central

30 July 2017

1 reference

based on heuristic

inferred from title

neoplastic stem cells

1 reference

based on heuristic

inferred from title

4

object named as

John M Asara

1 reference

Europe PubMed Central

30 July 2017

Marcia C. Haigis

5

object named as

Marcia C Haigis

1 reference

Europe PubMed Central

30 July 2017

author name string

Andreas Janzer

1

1 reference

Europe PubMed Central

30 July 2017

Natalie J German

2

1 reference

Europe PubMed Central

30 July 2017

Karina N Gonzalez-Herrera

3

1 reference

Europe PubMed Central

30 July 2017

Kevin Struhl

6

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

7 July 2014

1 reference

Europe PubMed Central

30 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

30 July 2017

111

1 reference

Europe PubMed Central

30 July 2017

10574-10579

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Europe PubMed Central

30 July 2017

29

1 reference

Europe PubMed Central

30 July 2017

Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

1 reference

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Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Role of organic cation/carnitine transporter 1 in uptake of phenformin and inhibitory effect on complex I respiration in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Influence of threonine metabolism on S-adenosylmethionine and histone methylation

1 reference

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28 July 2018

Distinct perturbation of the translatome by the antidiabetic drug metformin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Phenformin as prophylaxis and therapy in breast cancer xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Rotenone-mediated changes in intracellular coenzyme A thioester levels: implications for mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

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A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin induces unique biological and molecular responses in triple negative breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin and reduced risk of cancer in diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

On respiratory impairment in cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

28 July 2018

Metformin in cancer: translational challenges

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Investigating metformin for cancer prevention and treatment: the end of the beginning

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Metformin inhibits nuclear factor kappaB activation and decreases serum high-sensitivity C-reactive protein level in experimental atherogenesis of rabbits

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Effects of metformin or rosiglitazone on serum concentrations of homocysteine, folate, and vitamin B12 in patients with type 2 diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Metabolic profiles show specific mitochondrial toxicities in vitro in myotube cells.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1409844111

21 January 2018

Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4115496

29 October 2018

Metformin inhibits inflammatory response via AMPK-PTEN pathway in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25002509

12 December 2020

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10.1073/PNAS.1409844111

1 reference

Europe PubMed Central

30 July 2017

2014PNAS..11110574J

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release_ndq3s5eatfd6xaam3btboujdb4

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https://api.fatcat.wiki/v0/release/ndq3s5eatfd6xaam3btboujdb4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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