Novel library of selenocompounds as kinase modulators. (Q33973521)

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8 February 2020

title

Novel library of selenocompounds as kinase modulators (English)

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8 February 2020

1

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8 February 2020

Elena Ibáñez

2

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8 February 2020

Alfonso Calvo

3

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8 February 2020

Carmen Sanmartín

5

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8 February 2020

author name string

Juan Antonio Palop

4

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8 February 2020

language of work or name

English

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publication date

27 July 2011

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8 February 2020

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8 February 2020

volume

16

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8 February 2020

issue

8

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8 February 2020

page(s)

6349-6364

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Creative Commons Attribution 4.0 International

8 February 2020

copyright license

start time

27 July 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Deoxycholic acid and selenium metabolite methylselenol exert common and distinct effects on cell cycle, apoptosis, and MAP kinase pathway in HCT116 human colon cancer cells

1 reference

12 December 2020

Recent progess in phosphoinositide 3-kinases: oncogenic properties and prognostic and therapeutic implications

1 reference

12 December 2020

Kinase regulation by sulfur and selenium containing compounds.

1 reference

12 December 2020

Irreversible protein kinase inhibitors

1 reference

12 December 2020

Melanoma prevention using topical PBISe

1 reference

12 December 2020

Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy

1 reference

12 December 2020

Selenium decreases thyroid cancer cell growth by increasing expression of GADD153 and GADD34.

1 reference

12 December 2020

Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

1 reference

12 December 2020

Sodium selenite increases the activity of the tumor suppressor protein, PTEN, in DU-145 prostate cancer cells

1 reference

12 December 2020

The DNA-binding epidermal growth factor-receptor inhibitor PD153035 and other DNA-intercalating cytotoxic drugs reactivate the expression of the retinoic acid receptor-beta tumor-suppressor gene in breast cancer cells.

1 reference

12 December 2020

Antioxidant-prooxidant properties of a new organoselenium compound library.

1 reference

12 December 2020

Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells

1 reference

12 December 2020

Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors

1 reference

12 December 2020

Melanoma chemoprevention in skin reconstructs and mouse xenografts using isoselenocyanate-4.

1 reference

12 December 2020

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

12 December 2020

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

1 reference

12 December 2020

A novel activation-induced suicidal degradation mechanism for Akt by selenium.

1 reference

12 December 2020

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

1 reference

12 December 2020

Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.

1 reference

12 December 2020

5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells

1 reference

12 December 2020

Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases

1 reference

12 December 2020

Protein kinases and phosphatases as therapeutic targets in cancer.

1 reference

12 December 2020

PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression

1 reference

12 December 2020

Novel potent organoselenium compounds as cytotoxic agents in prostate cancer cells

1 reference

12 December 2020

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

1 reference

12 December 2020

Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?

1 reference

12 December 2020

Kinase mutations in human disease: interpreting genotype-phenotype relationships

1 reference

12 December 2020

Design, synthesis of symmetrical bivalent mimetics of annonaceous acetogenins and their cytotoxicities.

1 reference

12 December 2020

Present and future of PI3K pathway inhibition in cancer: perspectives and limitations

1 reference

12 December 2020

Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells

1 reference

12 December 2020

Molecular symmetry: a structural property frequently present in new cytotoxic and proapoptotic drugs.

1 reference

12 December 2020

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

1 reference

12 December 2020

Defining the role of mTOR in cancer

1 reference

12 December 2020

Selenium compounds activate early barriers of tumorigenesis

1 reference

12 December 2020

Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells

1 reference

12 December 2020

Synthesis and in vitro anticancer activities of some selenadiazole derivatives.

1 reference

12 December 2020

Advances in preclinical small molecules for the treatment of NSCLC.

1 reference

12 December 2020

D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.

1 reference

12 December 2020

Targeting Akt3 signaling in malignant melanoma using isoselenocyanates

1 reference

12 December 2020

TOR, a central controller of cell growth

1 reference

12 December 2020

Selectively nonselective kinase inhibition: striking the right balance

1 reference

12 December 2020

Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells

1 reference

12 December 2020

Selenocyanates and diselenides: a new class of potent antileishmanial agents

1 reference

12 December 2020

Insulin-like growth factor-1 receptor transactivation modulates the inflammatory and proliferative responses of neurotensin in human colonic epithelial cells

1 reference

12 December 2020

Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells

1 reference

12 December 2020

Synthesis and pharmacological screening of several aroyl and heteroaroyl selenylacetic acid derivatives as cytotoxic and antiproliferative agents.

1 reference

12 December 2020

Persistent p21Cip1 induction mediates G(1) cell cycle arrest by methylseleninic acid in DU145 prostate cancer cells.

1 reference

12 December 2020

Computational approach to the identification of novel Aurora-A inhibitors

1 reference

12 December 2020

Pharmacological inhibition of aurora-A but not aurora-B impairs interphase microtubule dynamics

1 reference

12 December 2020

The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.

1 reference

12 December 2020

High-throughput biochemical kinase selectivity assays: panel development and screening applications.

1 reference

12 December 2020

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

1 reference

12 December 2020

Tumor inhibition by sodium selenite is associated with activation of c-Jun NH2-terminal kinase 1 and suppression of beta-catenin signaling

1 reference

12 December 2020

Suppression of mTOR via Akt-dependent and -independent mechanisms in selenium-treated colon cancer cells: involvement of AMPKalpha1.

1 reference

12 December 2020

Targeting multiple kinases in glioblastoma multiforme

1 reference

12 December 2020

Tumor-intrinsic and -extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine kinase inhibitors

1 reference

12 December 2020

The suppression of prostate LNCaP cancer cells growth by Selenium nanoparticles through Akt/Mdm2/AR controlled apoptosis

1 reference

12 December 2020

Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates

1 reference

12 December 2020

Type I insulin-like growth factor receptor over-expression induces proliferation and anti-apoptotic signaling in a three-dimensional culture model of breast epithelial cells

1 reference

12 December 2020

10.3390/MOLECULES16086349

Identifiers

DOI

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8 February 2020

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mapped directly with Wikidata item

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8 February 2020

PubMed publication ID

21796074

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