Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model (Q34038257)

30 July 2017

title

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model (English)

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30 July 2017

main subject

hepatocellular carcinoma

1 reference

1 reference

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Touati Benoukraf

14

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Adam J. Dupuy

Adam J Dupuy

17

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Alistair G Rust

Alistair G Rust

3

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Richie Soong

Richie Soong

15

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Neal G. Copeland

24

Neal G Copeland

1 reference

30 July 2017

23

Nancy A Jenkins

1 reference

30 July 2017

19

George K Radda

1 reference

30 July 2017

18

Randy L Johnson

1 reference

30 July 2017

21

Lodewyk Fa Wessels

1 reference

30 July 2017

author name string

Emilie A Bard-Chapeau

1

1 reference

30 July 2017

Anh-Tuan Nguyen

2

1 reference

30 July 2017

Ahmed Sayadi

4

1 reference

30 July 2017

Philip Lee

5

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30 July 2017

Belinda Q Chua

6

1 reference

30 July 2017

Lee-Sun New

7

1 reference

30 July 2017

Johann de Jong

8

1 reference

30 July 2017

Jerrold M Ward

9

1 reference

30 July 2017

Christopher Ky Chin

10

1 reference

30 July 2017

Valerie Chew

11

1 reference

30 July 2017

Han Chong Toh

12

1 reference

30 July 2017

Jean-Pierre Abastado

13

1 reference

30 July 2017

Frederic A Bard

16

1 reference

30 July 2017

Eric Cy Chan

20

1 reference

30 July 2017

David J Adams

22

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30 July 2017

language of work or name

English

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publication date

8 December 2013

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30 July 2017

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30 July 2017

volume

46

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30 July 2017

issue

1

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30 July 2017

page(s)

24-32

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describes a project that uses

30 July 2017

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=4131144

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4131144

inferred from PubMed Central ID database lookup

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5 July 2018

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Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma

5 July 2018

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Targeting cancer metabolism: a therapeutic window opens

5 July 2018

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5 July 2018

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Cell of origin strongly influences genetic selection in a mouse model of T-ALL

5 July 2018

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DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival

5 July 2018

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MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma.

5 July 2018

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Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Identification of novel oncogenes and tumor suppressors in hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Zinc finger protein Zbtb20 is essential for postnatal survival and glucose homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

PTEN at the crossroad of metabolic diseases and cancer in the liver.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Analyzing real-time PCR data by the comparative C(T) method

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Genomic imprinting at the mammalian Dlk1-Dio3 domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

High throughput gene expression measurement with real time PCR in a microfluidic dynamic array

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning 1H NMR spectroscopy in conjunction with multivariate data analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Review of genetic and epigenetic alterations in hepatocarcinogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

From cell structure to transcription: Hippo forges a new path

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

An extracellular matrix microarray for probing cellular differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Gene expression patterns in human liver cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Neonatal hepatic steatosis by disruption of the adenosine kinase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

5 July 2018

The renaissance of GSK3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Cluster analysis and display of genome-wide expression patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Adenosine deaminase and adenosine kinase in rat hepatomas and kidney tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4131144

Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.

5 July 2018

1 reference

Downregulation of MAGI1 associates with poor prognosis of hepatocellular carcinoma.

21 January 2018

1 reference

Significance of dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expressions in hepatocellular carcinoma

21 January 2018

1 reference

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

21 January 2018

1 reference

In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model

21 January 2018

1 reference

Genetic variegation of clonal architecture and propagating cells in leukaemia

21 January 2018

1 reference

Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis.

21 January 2018

1 reference

Metabonomic profiles discriminate hepatocellular carcinoma from liver cirrhosis by ultraperformance liquid chromatography-mass spectrometry

21 January 2018

1 reference

TEL-AML1 preleukemic activity requires the DNA binding domain of AML1 and the dimerization and corepressor binding domains of TEL.

21 January 2018

1 reference

Mouse genome informatics (MGI) resources for pathology and toxicology

21 January 2018

1 reference

BioMart: driving a paradigm change in biological data management

21 January 2018

1 reference

Alterations of NFIA in chronic malignant myeloid diseases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24316982

12 December 2020

inferred from PubMed ID database lookup

Dihydrouracil dehydrogenase activity in normal, differentiating and regnerating liver and in hepatomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24316982

12 December 2020

inferred from PubMed ID database lookup

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24316982

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NG.2847

1 reference

30 July 2017

1 reference

30 July 2017

1 reference