Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate (Q34053079)

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English	Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate	scientific article

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scholarly article

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30 January 2020

Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate (English)

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30 January 2020

Charles D Anderson

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author name string

Deanna L Siow

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30 January 2020

Evgeny V Berdyshev

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30 January 2020

Anastasia Skobeleva

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Stuart M Pitson

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Binks W Wattenberg

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12 April 2010

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30 January 2020

Journal of Lipid Research

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51

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30 January 2020

2546-2559

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30 January 2020

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Orm family proteins mediate sphingolipid homeostasis

1 reference

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Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

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Sphingosine kinase as a regulator of calcium entry through autocrine sphingosine 1-phosphate signaling in thyroid FRTL-5 cells.

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Sphingosine-1-phosphate lyase in development and disease: sphingolipid metabolism takes flight

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Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway

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Principles of bioactive lipid signalling: lessons from sphingolipids

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Autocrine and paracrine roles of sphingosine-1-phosphate

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Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2.

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Intracellular generation of sphingosine 1-phosphate in human lung endothelial cells: role of lipid phosphate phosphatase-1 and sphingosine kinase 1.

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The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function

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Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

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Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

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The ins and outs of sphingolipid synthesis

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Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

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Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol.

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Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis.

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Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis

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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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VEGF induces S1P1 receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors

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Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis

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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

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Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors

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TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes

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Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation

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Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes

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Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

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A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development

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12 December 2020

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10.1194/JLR.M004374

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30 January 2020

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30 January 2020

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30 January 2020

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