Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants (Q34058079)

30 July 2017

Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants (English)

1 reference

30 July 2017

1

Özlem Demir

1 reference

Christopher Douglas Wassman

30 July 2017

4

object named as

Christopher D Wassman

1 reference

30 July 2017

6

G Wesley Hatfield

1 reference

30 July 2017

Richard Harold Lathrop

9

object named as

Richard H Lathrop

1 reference

30 July 2017

Roberta Baronio

2

1 reference

30 July 2017

Faezeh Salehi

3

1 reference

30 July 2017

Linda Hall

5

1 reference

30 July 2017

Richard Chamberlin

7

1 reference

30 July 2017

Peter Kaiser

8

1 reference

30 July 2017

Rommie E Amaro

10

1 reference

30 July 2017

20 October 2011

1 reference

PLOS Computational Biology

30 July 2017

1 reference

30 July 2017

7

1 reference

30 July 2017

10

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30 July 2017

e1002238

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Creative Commons Attribution 4.0 International

30 July 2017

start time

20 October 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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All-codon scanning identifies p53 cancer rescue mutations

5 July 2018

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5 July 2018

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Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning

5 July 2018

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Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

5 July 2018

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Restoration of p53 function leads to tumour regression in vivo

5 July 2018

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Modeling the therapeutic efficacy of p53 restoration in tumors

5 July 2018

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Structural basis for understanding oncogenic p53 mutations and designing rescue drugs

5 July 2018

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Comparison of multiple Amber force fields and development of improved protein backbone parameters

5 July 2018

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The P53 pathway: what questions remain to be explored?

5 July 2018

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Solution structure of p53 core domain: structural basis for its instability

5 July 2018

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5 July 2018

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5 July 2018

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A global suppressor motif for p53 cancer mutants

5 July 2018

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Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations

5 July 2018

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Live or let die: the cell's response to p53

5 July 2018

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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

5 July 2018

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Restoration of wild-type conformation and activity of a temperature-sensitive mutant of p53 (p53(V272M)) by the cytoprotective aminothiol WR1065 in the esophageal cancer cell line TE-1.

5 July 2018

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5 July 2018

Surfing the p53 network

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Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

5 July 2018

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5 July 2018

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5 July 2018

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Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

5 July 2018

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5 July 2018

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Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

5 July 2018

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Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Structure-based rescue of common tumor-derived p53 mutants

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22028641

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pharmacological rescue of mutant p53 conformation and function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22028641

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1002238

1 reference

journals/ploscb/DemirBSWHHCKLA11

30 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

30 July 2017

1 reference