Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning (Q33503650)

27 July 2017

Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning (English)

1 reference

27 July 2017

6

G Wesley Hatfield

1 reference

27 July 2017

Richard Harold Lathrop

8

object named as

Richard H Lathrop

1 reference

27 July 2017

Samuel A Danziger

1

1 reference

27 July 2017

Roberta Baronio

2

1 reference

27 July 2017

Lydia Ho

3

1 reference

27 July 2017

Linda Hall

4

1 reference

27 July 2017

Kirsty Salmon

5

1 reference

27 July 2017

Peter Kaiser

7

1 reference

27 July 2017

4 September 2008

1 reference

PLOS Computational Biology

27 July 2017

1 reference

27 July 2017

5

1 reference

27 July 2017

9

1 reference

27 July 2017

e1000498

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

4 September 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Biomedical discovery acceleration, with applications to craniofacial development

21 June 2018

1 reference

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Bayesian surprise attracts human attention

21 June 2018

1 reference

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Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

p53 Activation: a case against Sir.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Enzyme optimization: moving from blind evolution to statistical exploration of sequence-function space

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Protein engineering applications of industrially exploitable enzymes: Geobacillus stearothermophilus LDH and Candida methylica FDH.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

The screening of the second-site suppressor mutations of the common p53 mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Restoration of p53 function leads to tumour regression in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

A unified framework for image retrieval using keyword and visual features

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

p53 mutants: the achilles' heel of human cancers?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

UCSF Chimera--a visualization system for exploratory research and analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

A global suppressor motif for p53 cancer mutants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Restoring p53-dependent tumor suppression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Small molecules that reactivate mutant p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Rescuing the function of mutant p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Assessing the accuracy of prediction algorithms for classification: an overview

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

p53 mutations in human cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

The folding of an enzyme. I. Theory of protein engineering analysis of stability and pathway of protein folding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742196

Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000498

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000498

A method for localizing ligand binding pockets in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000498

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000498

21 January 2018

Gone but not forgotten

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000498

Analysis of void volumes in proteins and application to stability of the p53 tumour suppressor protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19756158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1000498

1 reference

journals/ploscb/DanzigerBHHSHKL09

27 July 2017

1 reference

DBLP Dataset 2021-01-02

release_7kmg6hza55ctrl7c5buwya65bi

28 January 2021

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7kmg6hza55ctrl7c5buwya65bi

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

2742196

1 reference

27 July 2017

1 reference