Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt). (Q34073898)

30 July 2017

title

Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt). (English)

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30 July 2017

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1

Ilaria Dalla Rosa

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Yves Pommier

6

object named as

Yves Pommier

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30 July 2017

Shar-Yin N Huang

2

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30 July 2017

Keli Agama

3

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30 July 2017

Salim Khiati

4

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30 July 2017

Hongliang Zhang

5

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30 July 2017

language of work or name

English

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publication date

5 May 2014

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Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

289

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30 July 2017

issue

26

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30 July 2017

page(s)

18595-18602

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Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria

30 July 2017

cites work

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Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mitochondrial topoisomerase I sites in the regulatory D-loop region of mitochondrial DNA.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.

5 July 2018

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Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

21 January 2018

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DNA cleavage assay for the identification of topoisomerase I inhibitors

21 January 2018

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Subcellular localization of the camptothecin analogues, topotecan and gimatecan

21 January 2018

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Clinical and molecular features of mitochondrial DNA depletion due to mutations in deoxyguanosine kinase.

21 January 2018

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Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

21 January 2018

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12 December 2020

Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin

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12 December 2020

Lipid bilayer partitioning and stability of camptothecin drugs

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12 December 2020

Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

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12 December 2020

Mechanism of mitochondrial DNA replication in mouse L-cells: Kinetics of synthesis and turnover of the initiation sequence

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12 December 2020

Identifiers

DOI

10.1074/JBC.M114.555367

1 reference

30 July 2017

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30 July 2017

1 reference