Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids (Q34126012)

31 July 2017

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title

Cytochrome P450-dependent metabolism of omega-6 and omega-3 long-chain polyunsaturated fatty acids (English)

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31 July 2017

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Cosima Arnold

1

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31 July 2017

Anne Konkel

series ordinal

2

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31 July 2017

Robert Fischer

series ordinal

3

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31 July 2017

Wolf-Hagen Schunck

series ordinal

4

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31 July 2017

1 May 2010

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31 July 2017

Pharmacological Reports

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31 July 2017

62

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31 July 2017

3

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31 July 2017

536-547

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Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Dietary (n-3) long-chain polyunsaturated fatty acids inhibit ischemia and reperfusion arrhythmias and infarction in rat heart not enhanced by ischemic preconditioning

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

The composition of food consumed by Greenland Eskimos.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Nitric oxide/cytochrome P450 interactions in cyclosporin A-induced effects in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Polyunsaturated fatty acids and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

N-3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Biochemical and molecular properties of the cytochrome P450 arachidonic acid monooxygenases.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

20-hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Metabolism of eicosapentaenoic and docosahexaenoic acids by recombinant human cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Dietary n-3 polyunsaturated fatty acids and direct renin inhibition improve electrical remodeling in a model of high human renin hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome P450 2C is an EDHF synthase in coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Epoxyeicosatrienoic acids, cell signaling and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Vascular cytochrome p450 enzymes: physiology and pathophysiology.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Prostaglandins and leukotrienes: advances in eicosanoid biology

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Effects of all CIS-5, 8,11,14,17 eicosapentaenoic acid and PGH3 on platelet aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Inhibitors of 20-HETE formation promote salt-sensitive hypertension in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome P450-dependent renal arachidonic acid metabolism in desoxycorticosterone acetate-salt hypertensive mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase gene deletion reduces survival after cardiac arrest and cardiopulmonary resuscitation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

20-Hydroxyeicosatetraenoic acid stimulates nuclear factor-kappaB activation and the production of inflammatory cytokines in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome p450 epoxygenase promotes human cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

The biochemistry of n-3 polyunsaturated fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Characterization and tissue distribution of a novel human cytochrome P450-CYP2U1.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

The inverse relation between fish consumption and 20-year mortality from coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Dietary fat and health: the evidence and the politics of prevention: careful use of dietary fats can improve life and prevent disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome P450-dependent eicosapentaenoic acid metabolites are novel BK channel activators

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Omega-3 polyunsaturated fatty acids and cardiovascular diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Failure to upregulate the adenosine2A receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Role of cytochrome P450-dependent transient receptor potential V4 activation in flow-induced vasodilatation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Stereospecific activation of cardiac ATP-sensitive K(+) channels by epoxyeicosatrienoic acids: a structural determinant study

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

A systematic review and meta-analysis of the impact of omega-3 fatty acids on selected arrhythmia outcomes in animal models

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Relaxing effects of 17(18)-EpETE on arterial and airway smooth muscles in human lung

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Effects of selective inhibition of cytochrome P-450 omega-hydroxylases and ischemic preconditioning in myocardial protection

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Inhibition of cytochrome P450omega-hydroxylase: a novel endogenous cardioprotective pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

1 reference

7 January 2021

Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

P-450 metabolites of arachidonic acid in the control of cardiovascular function

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Human CYP1A1 variants lead to differential eicosapentaenoic acid metabolite patterns

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Role of epoxyeicosatrienoic acids in protecting the myocardium following ischemia/reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Vascular cytochrome P450 4A expression and 20-hydroxyeicosatetraenoic acid synthesis contribute to endothelial dysfunction in androgen-induced hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Arachidonic acid cytochrome P450 epoxygenase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Vascular protective effects of cytochrome p450 epoxygenase-derived eicosanoids

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Low Na intake suppresses expression of CYP2C23 and arachidonic acid-induced inhibition of ENaC

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Biosynthesis and biological activity of leukotriene B5.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Oxidation of 5,8,11,14,17-eicosapentaenoic acid by hepatic and renal microsomes.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Use of red blood cell fatty-acid profiles as biomarkers in cardiac disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cardiovascular benefits of omega-3 fatty acids

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Endothelial dysfunction and hypertension in rats transduced with CYP4A2 adenovirus

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cyclic AMP-dependent modulation of cardiac L-type Ca2+ and transient outward K+ channel activities by epoxyeicosatrienoic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome P450: a novel system modulating Ca2+ channels and contraction in mammalian heart cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Enhancement of cardiac L-type Ca2+ currents in transgenic mice with cardiac-specific overexpression of CYP2J2

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Characterization of epoxyeicosatrienoic acid binding site in U937 membranes using a novel radiolabeled agonist, 20-125i-14,15-epoxyeicosa-8(Z)-enoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Cytochrome p-450 epoxygenase metabolites of docosahexaenoate potently dilate coronary arterioles by activating large-conductance calcium-activated potassium channels

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

EET homologs potently dilate coronary microvessels and activate BK(Ca) channels

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970311-X

7 January 2021

10.1016/S1734-1140(10)70311-X

Identifiers

DOI

1 reference

31 July 2017

1 reference