Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon (Q34189309)

31 July 2017

title

Specification of the NF-kappaB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK epsilon (English)

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31 July 2017

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Rita Moreno

1

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31 July 2017

Jürgen-Markus Sobotzik

series ordinal

2

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31 July 2017

Christian Schultz

series ordinal

3

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31 July 2017

M Lienhard Schmitz

series ordinal

4

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31 July 2017

language of work or name

English

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publication date

27 May 2010

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31 July 2017

published in

Nucleic Acids Research

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31 July 2017

volume

38

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31 July 2017

issue

18

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31 July 2017

page(s)

6029-6044

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Creative Commons Attribution-NonCommercial 2.5 Generic

31 July 2017

copyright license

start time

4 October 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Phosphorylation of NF-kappaB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination

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5 July 2018

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RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes

5 July 2018

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Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?

5 July 2018

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Shared principles in NF-kappaB signaling

5 July 2018

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Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65

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Genome-wide mapping of RELA(p65) binding identifies E2F1 as a transcriptional activator recruited by NF-kappaB upon TLR4 activation

5 July 2018

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An Atomic Model of the Interferon-β Enhanceosome

5 July 2018

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

5 July 2018

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5 July 2018

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PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

5 July 2018

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Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

5 July 2018

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Beyond IkappaBs: alternative regulation of NF-kappaB activity

5 July 2018

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Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin

5 July 2018

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Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity

5 July 2018

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The mechanisms of PML-nuclear body formation

5 July 2018

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Regulation and function of IKK and IKK-related kinases

5 July 2018

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Commonly dysregulated genes in murine APL cells

5 July 2018

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Keeping up NF-kappaB appearances: epigenetic control of immunity or inflammation-triggered epigenetics.

5 July 2018

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Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon

5 July 2018

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Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infections

5 July 2018

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Extending the nuclear roles of IkappaB kinase subunits

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Shaping alternative NF-kappaB-dependent gene expression programs: new clues to specificity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Quantitative models of nuclear transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

NF-kappaB: a multifaceted transcription factor regulated at several levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Genetic analysis of NF- B/Rel transcription factors defines functional specificities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Distribution of NF-kappaB-binding sites across human chromosome 22

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Triggering the interferon antiviral response through an IKK-related pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

The promyelocytic leukemia protein represses A20-mediated transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Duration of nuclear NF-kappaB action regulated by reversible acetylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Regulation of RelA subcellular localization by a putative nuclear export signal and p50.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Inhibition of NF-kappaB DNA binding by nitric oxide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Activation of NF-kappa B in vivo is regulated by multiple phosphorylations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2952868

Transient and selective NF-kappa B p65 serine 536 phosphorylation induced by T cell costimulation is mediated by I kappa B kinase beta and controls the kinetics of p65 nuclear import

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

Heme oxygenase-1 inhibits the expression of adhesion molecules associated with endothelial cell activation via inhibition of NF-kappaB RelA phosphorylation at serine 276.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

Regulation of c-Jun phosphorylation by the I kappa B kinase-epsilon complex in fibroblast-like synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ439

21 January 2018

Identifiers

DOI

10.1093/NAR/GKQ439

1 reference

31 July 2017

1 reference

31 July 2017

1 reference