FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging (Q34197553)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18799725%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

FoxO3a regulates hematopoietic homeostasis through a negative feedback pathway in conditions of stress or aging (English)

1 reference

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14 January 2020

6

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14 January 2020

author name string

Kana Miyamoto

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18799725%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Takeshi Miyamoto

2

1 reference

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14 January 2020

Reiko Kato

3

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14 January 2020

Akihiko Yoshimura

4

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14 January 2020

Noboru Motoyama

5

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14 January 2020

language of work or name

English

0 references

publication date

17 September 2008

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14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18799725%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

112

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14 January 2020

issue

12

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14 January 2020

page(s)

4485-4493

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FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system

14 January 2020

cites work

1 reference

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Stems cells and the pathways to aging and cancer

5 July 2018

1 reference

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Foxo3 is required for the regulation of oxidative stress in erythropoiesis

5 July 2018

1 reference

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Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification.

5 July 2018

1 reference

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The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

5 July 2018

1 reference

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Identification of a tumour suppressor network opposing nuclear Akt function

5 July 2018

1 reference

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Cell intrinsic alterations underlie hematopoietic stem cell aging.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Spred-2 suppresses aorta-gonad-mesonephros hematopoiesis by inhibiting MAP kinase activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Transforming growth factor beta 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Does functional depletion of stem cells drive aging?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Spred is a Sprouty-related suppressor of Ras signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Age-associated characteristics of murine hematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Bifurcation of osteoclasts and dendritic cells from common progenitors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954681

The Biology of Hematopoietic Stem Cells

28 October 2018

1 reference

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Hematopoietic stem cell quiescence maintained by p21cip1/waf1

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18799725

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2008-05-159848

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18799725%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18799725%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18799725

1 reference