SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. (Q51027830)

27 March 2018

title

SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis. (English)

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27 March 2018

author

Ben Croker

1

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27 March 2018

Nicos A. Nicola

13

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27 March 2018

Andrew W. Roberts

15

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27 March 2018

Kate D Sutherland

Kate D Sutherland

8

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Doug Hilton

Douglas J Hilton

12

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Donald Metcalf

2

Donald Metcalf

1 reference

27 March 2018

Lorraine Robb

3

Lorraine Robb

1 reference

27 March 2018

Sandra L Mifsud

5

Sandra Mifsud

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27 March 2018

author name string

Wei Wei

4

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27 March 2018

Ladina DiRago

6

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27 March 2018

Leonie A Cluse

7

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27 March 2018

Lynne Hartley

9

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27 March 2018

Emily Williams

10

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27 March 2018

Jian-Guo Zhang

11

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27 March 2018

Warren S Alexander

14

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27 March 2018

language of work or name

English

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publication date

1 February 2004

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27 March 2018

published in

Immunity

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27 March 2018

volume

20

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27 March 2018

page(s)

153-165

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27 March 2018

issue

2

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27 March 2018

Tyrosine residues of the granulocyte colony-stimulating factor receptor transmit proliferation and differentiation signals in murine bone marrow cells

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Suppressors of cytokine signalling (SOCS) in the immune system

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7 January 2021

TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex

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Suppressor of Cytokine Signaling-1 Attenuates the Duration of Interferon γ Signal Transductionin Vitroandin Vivo

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7 January 2021

SOCS3 negatively regulates IL-6 signaling in vivo

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7 January 2021

The Rac2 guanosine triphosphatase regulates B lymphocyte antigen receptor responses and chemotaxis and is required for establishment of B-1a and marginal zone B lymphocytes

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7 January 2021

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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VavCre transgenic mice: a tool for mutagenesis in hematopoietic and endothelial lineages.

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Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

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7 January 2021

Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

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7 January 2021

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1 reference

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7 January 2021

Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity

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7 January 2021

SOCS3 regulates the plasticity of gp130 signaling

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7 January 2021

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

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7 January 2021

SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

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7 January 2021

Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice

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7 January 2021

Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice

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7 January 2021

SOCS3 is essential in the regulation of fetal liver erythropoiesis

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7 January 2021

STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation

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7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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7 January 2021

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

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7 January 2021

Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

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7 January 2021

SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

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7 January 2021

G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood

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7 January 2021

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

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7 January 2021

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

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7 January 2021

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

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7 January 2021

Generalized lacZ expression with the ROSA26 Cre reporter strain

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

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7 January 2021

The Stat1 binding motif of the interferon-gamma receptor is sufficient to mediate Stat5 activation and its repression by SOCS3.

1 reference

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7 January 2021

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

1 reference

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7 January 2021

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

1 reference

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7 January 2021

10.1016/S1074-7613(04)00022-6

Identifiers

DOI

1 reference

27 March 2018

release_qlpr2deszbav3nohzweopvuoj4

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qlpr2deszbav3nohzweopvuoj4

24 November 2022

mapped directly with Wikidata item

PubMed ID

14975238

1 reference

27 March 2018