The aurora kinases in cell cycle and leukemia (Q34203062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

review article

1 reference

title

The aurora kinases in cell cycle and leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

3 references

3 April 2019

28 September 2019

10 December 2019

1 reference

28 September 2019

1 reference

10 December 2019

2

1 reference

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10 March 2020

author name string

B Goldenson

series ordinal

1

1 reference

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10 March 2020

language of work or name

English

0 references

publication date

17 March 2014

1 reference

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10 March 2020

4 references

3 April 2019

28 September 2019

10 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

34

1 reference

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10 March 2020

issue

5

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10 March 2020

page(s)

537-545

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https://scigraph.springernature.com/pub.10.1038/onc.2014.14

10 March 2020

exact match

0 references

cites work

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CD34⁺/CD38⁻ acute myelogenous leukemia cells aberrantly express Aurora kinase A.

5 July 2018

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Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia

5 July 2018

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Aurora B inhibitor barasertib and cytarabine exert a greater-than-additive cytotoxicity in acute myeloid leukemia cells

5 July 2018

1 reference

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Activity of histone deacetylase inhibitors and an Aurora kinase inhibitor in BCR-ABL-expressing leukemia cells: Combination of HDAC and Aurora inhibitors in BCR-ABL-expressing cells

5 July 2018

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A phase I schedule dependency study of the aurora kinase inhibitor MSC1992371A in combination with gemcitabine in patients with solid tumors

5 July 2018

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Occurrence and modulation of therapeutic targets of Aurora kinase inhibition in pediatric acute leukemia cells

5 July 2018

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An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia

5 July 2018

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Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

5 July 2018

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Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target

5 July 2018

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Conditional Aurora A deficiency differentially affects early mouse embryo patterning

5 July 2018

1 reference

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Phase I study of the Aurora B kinase inhibitor barasertib (AZD1152) to assess the pharmacokinetics, metabolism and excretion in patients with acute myeloid leukemia

5 July 2018

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Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL

5 July 2018

1 reference

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

5 July 2018

1 reference

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Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO-dependent mechanism

5 July 2018

1 reference

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Aurora kinase inhibitors: progress towards the clinic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Overcoming CML acquired resistance by specific inhibition of Aurora A kinase in the KCL-22 cell model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Overexpression of active Aurora-C kinase results in cell transformation and tumour formation

5 July 2018

1 reference

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Normal and malignant megakaryopoiesis

5 July 2018

1 reference

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Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

AT9283, a novel aurora kinase inhibitor, suppresses tumor growth in aggressive B-cell lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Shared and separate functions of polo-like kinases and aurora kinases in cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Molecular distinctions between Aurora A and B: a single residue change transforms Aurora A into correctly localized and functional Aurora B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function

5 July 2018

1 reference

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Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

5 July 2018

1 reference

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The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

5 July 2018

1 reference

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The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Fragment-based discovery of the pyrazol-4-yl urea (AT9283), a multitargeted kinase inhibitor with potent aurora kinase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A kinase is essential for bipolar spindle formation and early development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora A is essential for early embryonic development and tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Activating mutations in human acute megakaryoblastic leukemia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The Aurora kinase family in cell division and cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A: the maker and breaker of spindle poles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A kinase interacting protein 1 (AURKAIP1) promotes Aurora-A degradation through an alternative ubiquitin-independent pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A kinase and inhibitor-2 regulate the cyclin threshold for mitotic entry in Xenopus early embryonic cell cycles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Activating alleles of JAK3 in acute megakaryoblastic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora A, mitotic entry, and spindle bipolarity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Function and regulation of Maskin, a TACC family protein, in microtubule growth during mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Inhibition of Aurora A in response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A site specificity: a study with synthetic peptide substrates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora C is directly associated with Survivin and required for cytokinesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Chfr is required for tumor suppression and Aurora A regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Overexpression of Aurora-A potentiates HRAS-mediated oncogenic transformation and is implicated in oral carcinogenesis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Chromosomal passengers: the four-dimensional regulation of mitotic events

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

A gene atlas of the mouse and human protein-encoding transcriptomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora B regulates MCAK at the mitotic centromere

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The cellular geography of aurora kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Structural basis of Aurora-A activation by TPX2 at the mitotic spindle

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Identification of novel phosphorylation sites on Xenopus laevis Aurora A and analysis of phosphopeptide enrichment by immobilized metal-affinity chromatography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Function and regulation of Aurora/Ipl1p kinase family in cell division

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The spindle checkpoint: structural insights into dynamic signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cancer. Addiction to oncogenes--the Achilles heal of cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Role of chromosomal passenger complex in chromosome segregation and cytokinesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Acute promyelocytic leukemia: evolving therapeutic strategies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Mitotic kinases as regulators of cell division and its checkpoints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Downregulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Identification and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Endomitosis of human megakaryocytes are due to abortive mitosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

Cell cycle-dependent regulation of the human aurora B promoter

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Requirements for the destruction of human Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Destruction box-dependent degradation of aurora B is mediated by the anaphase-promoting complex/cyclosome and Cdh1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Human aurora-B binds to a proteasome alpha-subunit HC8 and undergoes degradation in a proteasome-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Dynamic association of a tumor amplified kinase, Aurora‐A, with the centrosome and mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Centrosomes promote timely mitotic entry in C. elegans embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Polymorphisms of STK15 (Aurora-A) gene and lung cancer risk in Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Gene amplification and overexpression of Aurora-C in breast and prostate cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Endomitotic megakaryocytes that form a bipolar spindle exhibit cleavage furrow ingression followed by furrow regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Endomitotic megakaryocytes form a midzone in anaphase but have a deficiency in cleavage furrow formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Megakaryocytes express functional Aurora-B kinase in endomitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Exome sequencing identifies putative drivers of progression of transient myeloproliferative disorder to AMKL in infants with Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

FLT3 mutation and expression did not adversely affect clinical outcome of childhood acute leukaemia: a study of 531 Southeast Asian children by the Ma-Spore study group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

A phase I dose-escalation study of MSC1992371A, an oral inhibitor of aurora and other kinases, in advanced hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

A Phase I study to assess the safety, pharmacokinetics and efficacy of barasertib (AZD1152), an Aurora B kinase inhibitor, in Japanese patients with advanced acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

The landscape of somatic mutations in Down syndrome-related myeloid disorders.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4167158

JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Repression of AIM-1 Kinase mRNA as Part of a Program of Genes Regulated by Mpl Ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Chromosomes take the lead in spindle assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Degradation of human Aurora-A protein kinase is mediated by hCdh1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Identification of a functional destruction box in the Xenopus laevis aurora-A kinase pEg2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Differential Functions of the Aurora-B and Aurora-C Kinases in Mammalian Spermatogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

MK-0457, a novel kinase inhibitor, is active in patients with chronic myeloid leukemia or acute lymphocytic leukemia with the T315I BCR-ABL mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Effects of the novel aurora kinase/JAK inhibitor, AT9283 and imatinib on Philadelphia positive cells in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.14

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24632603

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24632603%20AND%20SRC:MED&resulttype=core&format=json