Therapy-Induced Senescence in Cancer (Q34212773)

31 July 2017

title

Therapy-induced senescence in cancer (English)

1 reference

https://api.crossref.org/works/10.1093/JNCI/DJQ364

31 July 2017

Therapy-Induced Senescence in Cancer (English)

1 reference

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

17 July 2024

3

George Wilding

1 reference

31 July 2017

Jonathan A. Ewald

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

17 July 2024

Joshua A. Desotelle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

17 July 2024

David F. Jarrard

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

17 July 2024

language of work or name

English

0 references

publication date

21 September 2010

1 reference

full work available at URL

31 July 2017

https://academic.oup.com/jnci/article-pdf/102/20/1536/18085630/djq364.pdf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

http://jncicancerspectrum.oxfordjournals.org/cgi/content/abstract/102/20/1536

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20858887/?tool=EBI

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20858887/pdf/?tool=EBI

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

https://europepmc.org/articles/PMC2957429

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

https://europepmc.org/articles/PMC2957429?pdf=render

17 July 2024

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

https://doi.org/10.1093/jnci/djq364

17 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20858887

http://academic.oup.com/jnci/article-pdf/102/20/1536/18085630/djq364.pdf

17 July 2024

https://api.crossref.org/works/10.1093/JNCI/DJQ364

1 reference

Journal of the National Cancer Institute

17 July 2024

published in

1 reference

31 July 2017

volume

102

1 reference

31 July 2017

issue

20

1 reference

31 July 2017

page(s)

1536-1546

1 reference

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

31 July 2017

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5 July 2018

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Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1.

5 July 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

5 July 2018

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5 July 2018

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A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression

5 July 2018

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Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation

5 July 2018

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Synthesis and anticancer properties of water-soluble zinc ionophores

5 July 2018

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Living on a break: cellular senescence as a DNA-damage response

5 July 2018

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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

5 July 2018

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Chemokine signaling via the CXCR2 receptor reinforces senescence

5 July 2018

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

5 July 2018

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The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

5 July 2018

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Drug-induced senescence bystander proliferation in prostate cancer cells in vitro and in vivo

5 July 2018

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A chemotherapy-associated senescence bystander effect in breast cancer cells

5 July 2018

1 reference

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Free radicals and senescence

5 July 2018

1 reference

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Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

5 July 2018

1 reference

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New circulating biomarkers for prostate cancer

5 July 2018

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Cellular senescence: when bad things happen to good cells

5 July 2018

1 reference

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Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells.

5 July 2018

1 reference

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Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG

5 July 2018

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Mitochondrial fission and fusion mediators, hFis1 and OPA1, modulate cellular senescence

5 July 2018

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Heterochromatin and its relationship to cell senescence and cancer therapy

5 July 2018

1 reference

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

5 July 2018

1 reference

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Molecular dissection of formation of senescence-associated heterochromatin foci

5 July 2018

1 reference

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p63, cellular senescence and tumor development

5 July 2018

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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

5 July 2018

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Induction of senescence in MYCN amplified neuroblastoma cell lines by hydroxyurea

5 July 2018

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Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.

5 July 2018

1 reference

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Novel non-cytotoxic therapy in ovarian cancer: current status and future prospects

5 July 2018

1 reference

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Cellular senescence as a stress response

5 July 2018

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Coexpression of NRASQ61R and BRAFV600E in human melanoma cells activates senescence and increases susceptibility to cell-mediated cytotoxicity.

5 July 2018

1 reference

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Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes

5 July 2018

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Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group

5 July 2018

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Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

5 July 2018

1 reference

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p63: a new link between senescence and aging

5 July 2018

1 reference

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Lovastatin-induced RhoA modulation and its effect on senescence in prostate cancer cells

5 July 2018

1 reference

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The identification of senescence-specific genes during the induction of senescence in prostate cancer cells

5 July 2018

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

5 July 2018

1 reference

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Tumour biology: senescence in premalignant tumours

5 July 2018

1 reference

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The p53 pathway: positive and negative feedback loops

5 July 2018

1 reference

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Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?

5 July 2018

1 reference

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Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.

5 July 2018

1 reference

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The signals and pathways activating cellular senescence

5 July 2018

1 reference

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

5 July 2018

1 reference

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Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model.

5 July 2018

1 reference

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TGF-beta cytokines increase senescence-associated beta-galactosidase activity in human prostate basal cells by supporting differentiation processes, but not cellular senescence

5 July 2018

1 reference

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

5 July 2018

1 reference

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Reversal of human cellular senescence: roles of the p53 and p16 pathways

5 July 2018

1 reference

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Bcl-2 activates a programme of premature senescence in human carcinoma cells

5 July 2018

1 reference

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Tumor cell senescence in cancer treatment

5 July 2018

1 reference

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Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci

5 July 2018

1 reference

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Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53.

5 July 2018

1 reference

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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

5 July 2018

1 reference

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Induction of apoptosis in human replicative senescent fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells

5 July 2018

1 reference

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Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Role of cyclin-dependent kinase inhibitors in the growth arrest at senescence in human prostate epithelial and uroepithelial cells

5 July 2018

1 reference

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Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

5 July 2018

1 reference

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

5 July 2018

1 reference

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Senescent cells are resistant to death despite low Bcl-2 level

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Adenovirus-mediated overexpression of p15INK4B inhibits human glioma cell growth, induces replicative senescence, and inhibits telomerase activity similarly to p16INK4A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Tumor suppressors and oncogenes in cellular senescence.

5 July 2018

1 reference

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Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

5 July 2018

1 reference

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5 July 2018

1 reference

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Why are transformed cells immortal? Is the process reversible?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Quantitative assessment of markers for cell senescence.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

A change of strategy in the war on cancer.

28 October 2018

1 reference

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K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells.

28 October 2018

1 reference

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Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras-MAPK signaling in human cancer cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Differential regulation of apoptotic cell death in senescent human cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Caspase inhibition switches doxorubicin-induced apoptosis to senescence

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Characterization of epithelial senescence by serial analysis of gene expression: identification of genes potentially involved in prostate cancer.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

DNA damage is able to induce senescence in tumor cells in vitro and in vivo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Limited lifespan in somatic cell hybrids and cybrids.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957429

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents

28 October 2018

1 reference

12 December 2020

p16 INK4a can initiate an autonomous senescence program

1 reference

12 December 2020

p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factor

1 reference

12 December 2020

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

12 December 2020

Novel kinase inhibitors in renal cell carcinoma: progressive development of static agents

1 reference

12 December 2020

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

12 December 2020

Replicative potentials of various fusion products between WI-38 and SV40 transformed WI-38 cells and their components

1 reference

12 December 2020

Evaluation of combination chemotherapy and phase II agents in pancreatic adenocarcinoma. A Southwest Oncology Group study

1 reference

12 December 2020

p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53

1 reference

12 December 2020

Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia

1 reference

12 December 2020

Downregulation of caveolin-1 affects bleomycin-induced growth arrest and cellular senescence in A549 cells

1 reference

12 December 2020

Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition

1 reference

12 December 2020

Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells

1 reference

12 December 2020

Expression of SV40 T antigen in finite life-span hybrids of normal and SV40-transformed fibroblasts

1 reference

12 December 2020

Identifiers

DOI

10.1093/JNCI/DJQ364

1 reference

31 July 2017

1 reference

31 July 2017

1 reference