New insights into the treatment of multiple myeloma with histone deacetylase inhibitors (Q34224278)

31 July 2017

title

New insights into the treatment of multiple myeloma with histone deacetylase inhibitors (English)

1 reference

31 July 2017

1 reference

5

Paul G Richardson

1 reference

31 July 2017

7

Kenneth C Anderson

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31 July 2017

6

Teru Hideshima

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31 July 2017

2

Antonia Cagnetta

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31 July 2017

4

Franco Patrone

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31 July 2017

Michele Cea

1

1 reference

31 July 2017

Marco Gobbi

series ordinal

3

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31 July 2017

language of work or name

1 reference

1 January 2013

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Current Pharmaceutical Design

31 July 2017

published in

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31 July 2017

volume

19

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31 July 2017

issue

4

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31 July 2017

page(s)

734-744

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Immunoproteasome in cancer and neuropathologies: a new therapeutic target?

31 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6.

5 July 2018

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Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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The histone deacetylase inhibitor, PXD101, potentiates bortezomib-induced anti-multiple myeloma effect by induction of oxidative stress and DNA damage

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity

5 July 2018

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Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

5 July 2018

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5 July 2018

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Aggresome induction by proteasome inhibitor bortezomib and alpha-tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells

5 July 2018

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5 July 2018

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Histone deacetylase inhibitors repress the transactivation potential of hypoxia-inducible factors independently of direct acetylation of HIF-alpha

5 July 2018

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Chromatin control and cancer-drug discovery: realizing the promise

5 July 2018

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Histone deacetylase inhibitors: multifunctional anticancer agents.

5 July 2018

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5 July 2018

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A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors

5 July 2018

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The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

5 July 2018

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BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone

5 July 2018

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5 July 2018

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Analysis of histone deacetylase inhibitor, depsipeptide (FR901228), effect on multiple myeloma

5 July 2018

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5 July 2018

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The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.

5 July 2018

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

5 July 2018

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Controlling the double helix

5 July 2018

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The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

5 July 2018

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Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

5 July 2018

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5 July 2018

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Advances in therapy of multiple myeloma: lessons from acute leukemia

5 July 2018

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A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

5 July 2018

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Multiple myeloma: increasing evidence for a multistep transformation process

5 July 2018

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A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

5 July 2018

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5 July 2018

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Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.

28 October 2018

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Phase I trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) in patients with advanced multiple myeloma

28 October 2018

1 reference

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Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.

28 October 2018

1 reference

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Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?

28 October 2018

1 reference

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Histone deacetylase inhibitor depsipeptide (FK228) induces apoptosis in leukemic cells by facilitating mitochondrial translocation of Bax, which is enhanced by the proteasome inhibitor bortezomib.

28 October 2018

1 reference

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The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide

28 October 2018

1 reference

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NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma

28 October 2018

1 reference

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Molecular sequelae of histone deacetylase inhibition in human malignant B cells

28 October 2018

1 reference

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28 October 2018

1 reference

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StatBite: FDA oncology drug product approvals in 2009

28 October 2018

1 reference

12 December 2020

1 reference

12 December 2020

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

1 reference

12 December 2020

Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

1 reference

12 December 2020

Cardiac studies in patients treated with depsipeptide, FK228, in a phase II trial for T-cell lymphoma

1 reference

12 December 2020

Histone deacetylase inhibitors induce mitotic slippage

1 reference

12 December 2020

10.2174/138161213804581945

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference