Zinc and human health: an update (Q34231267)

31 July 2017

Zinc and human health: an update (English)

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31 July 2017

Christos T Chasapis

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Chara Spiliopoulou

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Chara A Spiliopoulou

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3

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author name string

Ariadni C Loutsidou

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2

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31 July 2017

Maria E Stefanidou

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4

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31 July 2017

language of work or name

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10 November 2011

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31 July 2017

Archives of Toxicology

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31 July 2017

86

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31 July 2017

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31 July 2017

521-534

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https://scigraph.springernature.com/pub.10.1007/s00204-011-0775-1

31 July 2017

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Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent

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Metals in Alzheimer's and Parkinson's diseases

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Crosstalk between L-type calcium channels and ZnT-1, a new player in rate-dependent cardiac electrical remodeling.

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Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling

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Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

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Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex

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Therapeutics for Alzheimer's disease based on the metal hypothesis

21 January 2018

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Zinc finger transcriptional activators of yeasts

21 January 2018

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A mutant human proinsulin is secreted from islets of Langerhans in increased amounts via an unregulated pathway

21 January 2018

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RING finger E(3) ubiquitin ligases: structure and drug discovery

21 January 2018

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Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

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Zinc homeostasis-regulating proteins: new drug targets for triggering cell fate.

21 January 2018

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In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion

21 January 2018

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Zinc deficiency-induced cell death

21 January 2018

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Zinc balance and medications commonly used in the management of heart failure

21 January 2018

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Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc deficiency impairs neuronal precursor cell proliferation and induces apoptosis via p53-mediated mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metallothionein: the multipurpose protein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

A zinc finger homeodomain transcription factor binds specific thyroid hormone response elements

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The role of assembly in insulin's biosynthesis

21 January 2018

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Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

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21 January 2018

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Zinc transporters and the cellular trafficking of zinc

21 January 2018

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Correlation between atrial ZnT-1 expression and atrial fibrillation in humans: a pilot study.

21 January 2018

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Plasticity of neuroendocrine-thymus interactions during aging.

21 January 2018

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Copper and zinc binding to amyloid-beta: coordination, dynamics, aggregation, reactivity and metal-ion transfer

21 January 2018

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Insulin-degrading enzyme: structure-function relationship and its possible roles in health and disease

21 January 2018

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Functions of the MDM2 oncoprotein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

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Introduction to NF-kappaB: players, pathways, perspectives

21 January 2018

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Copper, zinc, and Cu/Zn ratio in carcinoma of the gallbladder

21 January 2018

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Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling.

21 January 2018

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The immune system and the impact of zinc during aging

21 January 2018

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RING finger proteins: mediators of ubiquitin ligase activity

21 January 2018

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Zinc in innate and adaptive tumor immunity.

21 January 2018

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Advances in metal-induced oxidative stress and human disease

21 January 2018

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The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1.

21 January 2018

1 reference

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Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

High yield expression and NMR characterization of Arkadia E3 ubiquitin ligase RING-H2 finger domain

21 January 2018

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High precision NMR structure and function of the RING-H2 finger domain of EL5, a rice protein whose expression is increased upon exposure to pathogen-derived oligosaccharides

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc deficiency and immune function

21 January 2018

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Property of metallothionein as a Zn pool differs depending on the induced condition of metallothionein.

21 January 2018

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The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

21 January 2018

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Dual nanomolar and picomolar Zn(II) binding properties of metallothionein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Mutation spectrum of human SLC39A4 in a panel of patients with acrodermatitis enteropathica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Mammalian zinc transporters: nutritional and physiologic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metallothionein redox biology in the cytoprotective and cytotoxic functions of zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Copper and zinc levels in normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metals and amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc, metallothioneins, immune responses, survival and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc and immunoresistance to infection in aging: new biological tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc-bound metallothioneins as potential biological markers of ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metallothioneins (I+II) and thyroid-thymus axis efficiency in old mice: role of corticosterone and zinc supply

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Intracellular zinc homeostasis and zinc signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metallothioneins, oxidative stress and the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The Saccharomyces cerevisiae Crs5 Metallothionein metal-binding abilities and its role in the response to zinc overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Effect of transition metals on binding of p53 protein to supercoiled DNA and to consensus sequence in DNA fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The NMDA receptor as a therapeutic target in major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The essential toxin: impact of zinc on human health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc: role in immunity, oxidative stress and chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Dietary antioxidants: immunity and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Think zinc: New roles for zinc in the control of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Changes of serum-zinc in breast cancer (author's transl)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

In search of the tumour-suppressor functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Role of intracellular zinc in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Effects of long-term zinc treatment in Japanese patients with Wilson disease: efficacy, stability, and copper metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Serum zinc and copper levels in ischemic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Current zinc intake and risk of diabetes and coronary artery disease and factors associated with insulin resistance in rural and urban populations of North India

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc: a multipurpose trace element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Immersion autometallographic tracing of zinc ions in Alzheimer beta-amyloid plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The involvement of serotonergic system in the antidepressant effect of zinc in the forced swim test

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Movement of zinc and its functional significance in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Trace elements in human physiology and pathology: zinc and metallothioneins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

A distinct role in breast cancer for two LIV-1 family zinc transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Effects of angiotensin-converting enzyme inhibitors (ACE i) on zinc metabolism in patients with heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The role of zinc in caspase activation and apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The function of metallothionein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

New perspective on zinc biochemistry: cocatalytic sites in multi-zinc enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Thyroid hormone regulates neurotransmitter release in neonatal rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Metallothioneins: new functional and structural insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc for the treatment of diarrhoea: effect on diarrhoea morbidity, mortality and incidence of future episodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

A novel member of a zinc transporter family is defective in acrodermatitis enteropathica

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc overload enhances APP cleavage and Aβ deposition in the Alzheimer mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zn(2+): a novel ionic mediator of neural injury in brain disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc inhibits interleukin-1-dependent T cell stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc deficiency induces enhanced depression-like behaviour and altered limbic activation reversed by antidepressant treatment in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Chronic heart failure and micronutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc deficiency depresses p21 gene expression: inhibition of cell cycle progression is independent of the decrease in p21 protein level in HepG2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Zinc is a novel intracellular second messenger

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Divalent metal transporter 1 is involved in amyloid precursor protein processing and Abeta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

Elevation of zinc transporter ZnT3 protein in the cerebellar cortex of the AbetaPP/PS1 transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-011-0775-1

10.1007/S00204-011-0775-1

21 January 2018

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DOI

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31 July 2017

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