Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice (Q34307101)

1 August 2017

title

Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice (English)

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1 August 2017

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Jeffery D Molkentin

4

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author name string

Erin R Wissing

series ordinal

1

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1 August 2017

Douglas P Millay

series ordinal

2

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1 August 2017

Grégoire Vuagniaux

series ordinal

3

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1 August 2017

publication date

15 July 2010

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1 August 2017

number of pages

8

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inferred from page(s)

published in

Neuromuscular Disorders

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1 August 2017

volume

20

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1 August 2017

issue

11

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1 August 2017

page(s)

753-760

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describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2980760/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Cyclosporine A treatment for Ullrich congenital muscular dystrophy: a cellular study of mitochondrial dysfunction and its rescue

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Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy

6 July 2018

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Cyclosporin A corrects mitochondrial dysfunction and muscle apoptosis in patients with collagen VI myopathies

6 July 2018

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Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

6 July 2018

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The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria.

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6 July 2018

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6 July 2018

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6 July 2018

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Increased protein degradation results from elevated free calcium levels found in muscle from mdx mice

6 July 2018

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The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice.

28 October 2018

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Bone mineral density and bone metabolism in Duchenne muscular dystrophy

28 October 2018

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Steroids in Duchenne muscular dystrophy: from clinical trials to genomic research

28 October 2018

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Cyclosporine increases muscular force generation in Duchenne muscular dystrophy.

28 October 2018

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The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore.

28 October 2018

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Critical evaluation of cytosolic calcium determination in resting muscle fibres from normal and dystrophic (mdx) mice

28 October 2018

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12 December 2020

Membrane potential, resting calcium and calcium transients in isolated muscle fibres from normal and dystrophic mice

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12 December 2020

Prednisone can protect against exercise-induced muscle damage

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12 December 2020

Deflazacort increases laminin expression and myogenic repair, and induces early persistent functional gain in mdx mouse muscular dystrophy

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12 December 2020

10.1016/J.NMD.2010.06.016

Identifiers

DOI

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1 August 2017

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1 August 2017

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