Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells (Q34331407)

1 August 2017

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells (English)

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1 August 2017

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Markus Kleinewietfeld

object named as

Markus Kleinewietfeld

1

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Dominik N. Muller

object named as

Dominik N Muller

7

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David A. Hafler

8

object named as

David A Hafler

1 reference

1 August 2017

Arndt Manzel

2

1 reference

1 August 2017

Jens Titze

3

1 reference

1 August 2017

Heda Kvakan

4

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1 August 2017

Nir Yosef

5

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1 August 2017

Ralf A Linker

6

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1 August 2017

language of work or name

English

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publication date

6 March 2013

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1 August 2017

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1 August 2017

496

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1 August 2017

7446

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1 August 2017

518-522

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https://scigraph.springernature.com/pub.10.1038/nature11868

1 August 2017

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cites work

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6 July 2018

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6 July 2018

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Activation of p38 MAPK in CD4 T cells controls IL-17 production and autoimmune encephalomyelitis

6 July 2018

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RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

6 July 2018

1 reference

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The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.

6 July 2018

1 reference

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

6 July 2018

1 reference

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MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development

6 July 2018

1 reference

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Hypertonic stress regulates T cell function via pannexin-1 hemichannels and P2X receptors

6 July 2018

1 reference

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RNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels

6 July 2018

1 reference

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Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system

6 July 2018

1 reference

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Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity.

6 July 2018

1 reference

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Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents.

6 July 2018

1 reference

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Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism

6 July 2018

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Salt intakes around the world: implications for public health.

6 July 2018

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Transcriptional regulatory networks in Th17 cell differentiation

6 July 2018

1 reference

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

6 July 2018

1 reference

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Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5

6 July 2018

1 reference

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6 July 2018

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Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension

6 July 2018

1 reference

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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

6 July 2018

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IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

6 July 2018

1 reference

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Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors

6 July 2018

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6 July 2018

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

6 July 2018

1 reference

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p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

6 July 2018

1 reference

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Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Osmotic regulation of cytokine synthesis in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Hypertonic saline enhances cellular immune function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

h-sgk Serine-Threonine Protein Kinase as Transcriptional Target of p38/MAP Kinase pathway in HepG2 Human Hepatoma Cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746493

The importance of population-wide sodium reduction as a means to prevent cardiovascular disease and stroke: a call to action from the American Heart Association

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23467095

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

h-sgk serine-threonine protein kinase gene as transcriptional target of transforming growth factor beta in human intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23467095

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11868

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference