Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury. (Q34336370)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Metabolism, energetics, and lipid biology in the podocyte - cellular cholesterol-mediated glomerular injury (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1

1 reference

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22 February 2020

author name string

Christopher E Pedigo

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Armando J Mendez

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

14 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

Frontiers in Endocrinology

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

169

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

Renal involvement in Neimann-Pick Disease

22 February 2020

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6 July 2018

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Deficiency of a transcriptional regulator, inhibitor of differentiation 3, induces glomerulonephritis in apolipoprotein E-deficient mice: a model linking hyperlipidemia and renal disease

6 July 2018

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HMG-CoA reductase activation and urinary pellet cholesterol elevations in acute kidney injury

6 July 2018

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6 July 2018

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6 July 2018

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Macrophage cholesterol homeostasis and metabolic diseases: critical role of cholesteryl ester mobilization

6 July 2018

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Lipid disorders and their relevance to outcomes in chronic kidney disease

6 July 2018

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Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis

6 July 2018

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Interleukin-1β enhances the intracellular accumulation of cholesterol by up-regulating the expression of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase in podocytes

6 July 2018

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Association of trypanolytic ApoL1 variants with kidney disease in African Americans

6 July 2018

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Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene

6 July 2018

1 reference

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Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1

6 July 2018

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Weekly cyclodextrin administration normalizes cholesterol metabolism in nearly every organ of the Niemann-Pick type C1 mouse and markedly prolongs life.

6 July 2018

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Defective cholesterol trafficking in Niemann-Pick C-deficient cells

6 July 2018

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Intercapillary Lesions in the Glomeruli of the Kidney

6 July 2018

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Diabetes reduces the cholesterol exporter ABCA1 in mouse macrophages and kidneys

6 July 2018

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Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells

6 July 2018

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Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse

6 July 2018

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6 July 2018

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Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

6 July 2018

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Regulation of HMG-CoA reductase expression by hypoxia

6 July 2018

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Mechanisms of disease: the hypoxic tubular hypothesis of diabetic nephropathy

6 July 2018

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HIF activation protects from acute kidney injury

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway

6 July 2018

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Experimental glomerulopathy alters renal cortical cholesterol, SR-B1, ABCA1, and HMG CoA reductase expression

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Etiological significance of apolipoprotein E mutations in lipoprotein glomerulopathy

6 July 2018

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Lipid abnormalities in the nephrotic syndrome: the therapeutic role of statins.

6 July 2018

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6 July 2018

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Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation

6 July 2018

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Renal cholesterol accumulation: a durable response after acute and subacute renal insults

6 July 2018

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Cholesterol, a cell size-dependent signal that regulates glucose metabolism and gene expression in adipocytes

6 July 2018

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Analysis of glomerulosclerosis and atherosclerosis in lecithin cholesterol acyltransferase-deficient mice.

6 July 2018

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CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere

6 July 2018

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Functional loss of ABCA1 in mice causes severe placental malformation, aberrant lipid distribution, and kidney glomerulonephritis as well as high-density lipoprotein cholesterol deficiency

6 July 2018

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

6 July 2018

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Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

6 July 2018

1 reference

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Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm

6 July 2018

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A novel human apolipoprotein (apoM)

6 July 2018

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Megalin knockout mice as an animal model of low molecular weight proteinuria.

6 July 2018

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

6 July 2018

1 reference

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A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy

6 July 2018

1 reference

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

6 July 2018

1 reference

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

6 July 2018

1 reference

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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

6 July 2018

1 reference

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Nephrin is specifically located at the slit diaphragm of glomerular podocytes

6 July 2018

1 reference

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

6 July 2018

1 reference

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Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis

6 July 2018

1 reference

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Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

6 July 2018

1 reference

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Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency.

6 July 2018

1 reference

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A 10-bp deletion in the apolipoprotein epsilon gene causing apolipoprotein E deficiency and severe type III hyperlipoproteinemia.

6 July 2018

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Renal apolipoproteins in nephrotic rats

6 July 2018

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Lipoprotein metabolism and renal failure

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Renal failure in familial lecithin: cholesterol acyltransferase deficiency

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Biosynthesis of apolipoprotein B in rooster kidney, intestine, and liver.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Apolipoprotein E synthesis in human kidney, adrenal gland, and liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Type 3 hyperlipoproteinemia with mesangial foam cells in renal glomeruli

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency. Further studies of very low and low density lipoprotein abnormalities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Saturated free fatty acid toxicity. II. Lipid accumulation, ultrastructural alterations, and toxicity in mammalian cells in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Lipid accumulation of hypoxic tissue culture cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

The pathology of Tangier disease. A light and electron microscopic study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

A founder haplotype of APOE-Sendai mutation associated with lipoprotein glomerulopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Virus-mediated transduction of apolipoprotein E (ApoE)-sendai develops lipoprotein glomerulopathy in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Lipoprotein glomerulopathy induced by ApoE-Sendai is different from glomerular lesions in aged apoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Mesangial expansion associated with glomerular endothelial cell activation and macrophage recruitment is developing in hyperlipidaemic apoE null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Apolipoprotein E in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Baboon lecithin cholesterol acyltransferase (LCAT): cDNA sequences of two alleles, evolution, and gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Disruption of the murine lecithin:cholesterol acyltransferase gene causes impairment of adrenal lipid delivery and up-regulation of scavenger receptor class B type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

A novel in vivo lecithin-cholesterol acyltransferase (LCAT)-deficient mouse expressing predominantly LpX is associated with spontaneous glomerulopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

The NP-C gene: a key to pathways of intracellular cholesterol transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Protective effects of aliskiren and valsartan in mice with diabetic nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Anti-inflammatory effects of short-term pioglitazone therapy in men with advanced diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Effects of atorvastatin on kidney outcomes and cardiovascular disease in patients with diabetes: an analysis from the Collaborative Atorvastatin Diabetes Study (CARDS).

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Niacin improves renal lipid metabolism and slows progression in chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Chronic intermittent hypoxia is a major trigger for non-alcoholic fatty liver disease in morbid obese.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Hypoxia and non-alcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

NMR identifies atherogenic lipoprotein abnormalities in early diabetic nephropathy that are unrecognized by conventional analysis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Apolipoprotein E Sendai (arginine 145-->proline): a new variant associated with lipoprotein glomerulopathy

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Synthesis of apolipoprotein AI by peripheral tissues of the rooster. A possible mechanism of cellular cholesterol efflux.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Sturucture of an abnormal plasma lipoprotein (LP-X) characterizing obstructive jaundice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4196552

Bradykinin receptor 1 activation exacerbates experimental focal and segmental glomerulosclerosis

27 October 2018

1 reference

https://api.crossref.org/works/10.3389%2FFENDO.2014.00169

Identification of the abnormal cholestatic lipoprotein (LP-X) in familial lecithin:Cholesterol acyltransferase deficiency

21 January 2018

1 reference

12 December 2020

Secretion of apoB- and apoA-I-containing lipoproteins by chick kidney

1 reference

12 December 2020

Severe hyperlipidemia causes impaired renin-angiotensin system function in apolipoprotein E deficient mice

1 reference

12 December 2020

Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity

1 reference

12 December 2020

Characteristic, polymorphism and expression distribution of LCAT gene in a Mongolian gerbil model for hyperlipidemia

1 reference

12 December 2020

Familial serum-cholesterol esterification failure. A new inborn error of metabolism

1 reference

12 December 2020

Hypoxia Converts Human Macrophages Into Triglyceride-Loaded Foam Cells

1 reference

12 December 2020

Acquired lecithin:cholesterol acyltransferase deficiency as a major factor in lowering plasma HDL levels in chronic kidney disease

1 reference

12 December 2020

Cholesterol and lipid disturbances in renal disease: the natural history of uremic dyslipidemia and the impact of hemodialysis and continuous ambulatory peritoneal dialysis

1 reference

12 December 2020

Getting a foothold in nephrotic syndrome

1 reference

12 December 2020

The polysaccharide fraction of Propionibacterium acnes modulates the development of experimental focal segmental glomerulosclerosis

1 reference

12 December 2020

Lipid abnormalities in renal disease

1 reference

12 December 2020

Decreased cellular cholesterol efflux is a common cause of familial hypoalphalipoproteinemia: role of the ABCA1 gene mutations

1 reference

12 December 2020

Renal injury in apolipoprotein E-deficient mice

1 reference

12 December 2020

Lipoprotein glomerulopathy: first report in a Chinese male

1 reference

12 December 2020

Receptor mediated uptake of apo B and apo E rich lipoproteins by human glomerular epithelial cells

1 reference

12 December 2020

Increased lipoprotein-remnant formation in chronic renal failure

1 reference

12 December 2020

Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol

1 reference

12 December 2020

Membranoproliferative glomerulonephritis type II and Niemann-Pick disease type C

1 reference

12 December 2020

Estimation of oxidative stress markers in chronic kidney disease

1 reference

12 December 2020

Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome

1 reference

12 December 2020

Apolipoprotein E2, renal failure and lipid abnormalities in non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Apolipoprotein E polymorphism in IgA nephropathy

1 reference

12 December 2020

Apolipoprotein E4 reduces risk of diabetic nephropathy in patients with NIDDM

1 reference

12 December 2020

Control of fatty acid metabolism in ischemic and hypoxic hearts

1 reference

12 December 2020

Nephropathy of familial lecithin-cholesterol acyltransferase deficiency: report of a case

1 reference

12 December 2020

Identifiers

DOI

10.3389/FENDO.2014.00169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

release_3uwayftm4vamrkae6bu3bprdlq

22 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3uwayftm4vamrkae6bu3bprdlq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25352833%20AND%20SRC:MED&resulttype=core&format=json