DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors (Q34359769)

1 August 2017

title

DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors (English)

1 reference

1 August 2017

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Krisztina Arató

2

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Xavier Altafaj

Xavier Altafaj

José M Fernández-Fernández

9

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José M Fernández-Fernández

3

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Susana de la Luna

Susana de la Luna

8

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Isidro Ferrer

7

Isidre Ferrer

1 reference

1 August 2017

Cristina Grau

1

1 reference

1 August 2017

Aitana Valderrama

4

1 reference

1 August 2017

Carlos Sindreu

5

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1 August 2017

Cristina Fillat

6

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1 August 2017

publication date

17 October 2014

1 reference

Frontiers in Cellular Neuroscience

1 August 2017

published in

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1 August 2017

volume

8

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1 August 2017

page(s)

331

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Activity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinase

1 August 2017

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Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spines

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Triplication of DYRK1A causes retinal structural and functional alterations in Down syndrome

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6 July 2018

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6 July 2018

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Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors

6 July 2018

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Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour

6 July 2018

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Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.

6 July 2018

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Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

6 July 2018

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Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.

6 July 2018

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Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

6 July 2018

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Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.

6 July 2018

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Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

6 July 2018

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Cdk5 regulates the phosphorylation of tyrosine 1472 NR2B and the surface expression of NMDA receptors.

6 July 2018

1 reference

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Regulation of NMDA receptors by phosphorylation

6 July 2018

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NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

6 July 2018

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DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding

6 July 2018

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PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating

6 July 2018

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Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

6 July 2018

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6 July 2018

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The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2.

6 July 2018

1 reference

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Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand

6 July 2018

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Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

6 July 2018

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Src kinases: a hub for NMDA receptor regulation

6 July 2018

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Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Dyrk1A expression pattern supports specific roles of this kinase in the adult central nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Subunit-specific NMDA receptor trafficking to synapses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Regulation of NMDA receptors by cyclin-dependent kinase-5

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Protein kinase C activation modulates alpha-calmodulin kinase II binding to NR2A subunit of N-methyl-D-aspartate receptor complex.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Synaptic NMDA receptor channels have a low open probability.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

High probability opening of NMDA receptor channels by L-glutamate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4201086

MNB/DYRK1A phosphorylation regulates the interactions of synaptojanin 1 with endocytic accessory proteins

6 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Acute injections of the NMDA receptor antagonist memantine rescue performance deficits of the Ts65Dn mouse model of Down syndrome on a fear conditioning test.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Object recognition memory is conserved in Ts1Cje, a mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

PKC site mutations reveal differential modulation by insulin of NMDA receptors containing NR2A or NR2B subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Subunit-specific regulation of NMDA receptor endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Endocytosis and degradative sorting of NMDA receptors by conserved membrane-proximal signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFNCEL.2014.00331

Specificity determinants of substrate recognition by the protein kinase DYRK1A

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25368549

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FNCEL.2014.00331

1 reference

1 August 2017

1 reference

1 August 2017

1 reference