Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk (Q34365708)

1 August 2017

title

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk (English)

1 reference

1 August 2017

1 reference

Wenqiang Cao

1

1 reference

1 August 2017

Xiaoling Li

2

1 reference

1 August 2017

Shanyuan Zheng

3

1 reference

1 August 2017

Wenjie Zheng

4

1 reference

1 August 2017

Yum-Shing Wong

5

1 reference

1 August 2017

Tianfeng Chen

6

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1 August 2017

language of work or name

English

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publication date

1 September 2014

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1 August 2017

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1 August 2017

volume

5

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1 August 2017

issue

17

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1 August 2017

page(s)

7431-7445

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Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling

1 August 2017

cites work

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6 July 2018

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6 July 2018

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ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins

6 July 2018

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Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3.

6 July 2018

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In vivo radioprotection studies of 3,3'-diselenodipropionic acid, a selenocystine derivative

6 July 2018

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Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation

6 July 2018

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Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation

6 July 2018

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Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation

6 July 2018

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Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway

6 July 2018

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Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative

6 July 2018

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Overcoming apoptosis deficiency of melanoma-hope for new therapeutic approaches

6 July 2018

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Clearing the TRAIL for Cancer Therapy

6 July 2018

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6 July 2018

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Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates

6 July 2018

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Chemotherapy for metastatic melanoma: time for a change?

6 July 2018

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Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

6 July 2018

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Selenomethionine induces p53 mediated cell cycle arrest and apoptosis in human colon cancer cells.

6 July 2018

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Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells

6 July 2018

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6 July 2018

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6 July 2018

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Recent advances in understanding the cell death pathways activated by anticancer therapy

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Recent advances in melanoma biology

6 July 2018

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Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds

6 July 2018

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Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

6 July 2018

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Chemical sensitization and regulation of TRAIL-induced apoptosis in a panel of B-lymphocytic leukaemia cell lines

6 July 2018

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A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

6 July 2018

1 reference

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Activation of the PI3K/Akt pathway and chemotherapeutic resistance

6 July 2018

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6 July 2018

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6 July 2018

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Live or let die: the cell's response to p53

6 July 2018

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6 July 2018

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Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

6 July 2018

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HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

6 July 2018

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Regulation of PTEN transcription by p53

6 July 2018

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6 July 2018

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Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4202134

The importance of selenium to human health

6 July 2018

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6 July 2018

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Cellular survival: a play in three Akts

6 July 2018

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6 July 2018

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

6 July 2018

1 reference

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

6 July 2018

1 reference

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Anti-apoptotic, anti-inflammatory, and immunomodulatory activities of 3,3'-diselenodipropionic acid in mice exposed to whole body γ-radiation.

6 July 2018

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Akt enhances Mdm2-mediated ubiquitination and degradation of p53.

27 October 2018

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Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

27 October 2018

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Generation of Putative Intrastrand Cross-Links and Strand Breaks in DNA by Transition Metal Ion-Mediated Oxygen Radical Attack

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25277183

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.2008

0 references

PMC publication ID

4202134

1 reference

1 August 2017

1 reference