AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice (Q34383015)

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Language	Label	Description	Also known as
English	AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice	scientific article

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scholarly article

1 reference

Europe PubMed Central

1 August 2017

AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice (English)

1 reference

Europe PubMed Central

1 August 2017

amyotrophic lateral sclerosis

1 reference

based on heuristic

inferred from title

author name string

James C Dodge

1

1 reference

Europe PubMed Central

1 August 2017

Christopher M Treleaven

2

1 reference

Europe PubMed Central

1 August 2017

Jonathan A Fidler

3

1 reference

Europe PubMed Central

1 August 2017

Mark Hester

4

1 reference

Europe PubMed Central

1 August 2017

Amanda Haidet

5

1 reference

Europe PubMed Central

1 August 2017

Chalonda Handy

6

1 reference

Europe PubMed Central

1 August 2017

Meghan Rao

7

1 reference

Europe PubMed Central

1 August 2017

Amy Eagle

8

1 reference

Europe PubMed Central

1 August 2017

Jennifer C Matthews

9

1 reference

Europe PubMed Central

1 August 2017

Tatyana V Taksir

10

1 reference

Europe PubMed Central

1 August 2017

Seng H Cheng

11

1 reference

Europe PubMed Central

1 August 2017

Lamya S Shihabuddin

12

1 reference

Europe PubMed Central

1 August 2017

Brian K Kaspar

13

1 reference

Europe PubMed Central

1 August 2017

publication date

21 September 2010

1 reference

Europe PubMed Central

1 August 2017

Molecular Therapy

1 reference

Europe PubMed Central

1 August 2017

18

1 reference

Europe PubMed Central

1 August 2017

2075-2084

1 reference

Europe PubMed Central

1 August 2017

12

1 reference

Europe PubMed Central

1 August 2017

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

IGF-1:tetanus toxin fragment C fusion protein improves delivery of IGF-1 to spinal cord but fails to prolong survival of ALS mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Design, power, and interpretation of studies in the standard murine model of ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Beneficial effects of intrathecal IGF-1 administration in patients with amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Recombinant AAV-mediated gene delivery to the central nervous system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Age-related morphologic changes of the central canal of the human spinal cord

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Efficient and stable adeno-associated virus-mediated transduction in the skeletal muscle of adult immunocompetent mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Experimental rationale for the therapeutic use of neurotrophins in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

6 July 2018

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Functional correction of CNS phenotypes in a lysosomal storage disease model using adeno-associated virus type 4 vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997594

27 October 2018

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of spinal motor neuron death by insulin-like growth factor-1 associating with the signal transduction systems in SODG93A transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcutaneous IGF-1 is not beneficial in 2-year ALS trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted retrograde gene delivery for neuronal protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erratum: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20859261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MT.2010.206

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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