Different ligands-different receptor conformations: modeling of the hER alpha LBD in complex with agonists and antagonists (Q34405638)

2 August 2017

1 reference

title

Different ligands-different receptor conformations: modeling of the hER alpha LBD in complex with agonists and antagonists (English)

1 reference

2 August 2017

Egner U

1

1 reference

2 August 2017

Heinrich N

2

1 reference

2 August 2017

Ruff M

3

1 reference

2 August 2017

Gangloff M

4

1 reference

2 August 2017

Mueller-Fahrnow A

5

1 reference

2 August 2017

Wurtz JM

6

1 reference

2 August 2017

publication date

1 November 2001

1 reference

Medicinal Research Reviews

2 August 2017

published in

1 reference

2 August 2017

volume

21

1 reference

2 August 2017

issue

6

1 reference

2 August 2017

page(s)

523-539

1 reference

The nuclear receptor ligand-binding domain: structure and function

2 August 2017

cites work

1 reference

Ligand-binding domain of estrogen receptors

21 January 2018

1 reference

A structural biologist's view of the oestrogen receptor.

21 January 2018

1 reference

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

21 January 2018

1 reference

Studies on heterocycle-based pure estrogen antagonists.

21 January 2018

1 reference

Crystal structure of a mutant hERalpha ligand-binding domain reveals key structural features for the mechanism of partial agonism

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

Detection, delineation, measurement and display of cavities in macromolecular structures

21 January 2018

1 reference

The molecular surface package

21 January 2018

1 reference

Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

1 reference

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

21 January 2018

1 reference

Structural insights into the mode of action of a pure antiestrogen

21 January 2018

1 reference

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

21 January 2018

1 reference

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

Structure and specificity of nuclear receptor-coactivator interactions

21 January 2018

1 reference

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

21 January 2018

1 reference

Overexpression, purification, and crystal structure of native ER alpha LBD

21 January 2018

1 reference

Comparative QSAR analysis of estrogen receptor ligands

21 January 2018

1 reference

The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

21 January 2018

1 reference

RU 58,668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice

21 January 2018

1 reference

Rational discovery of novel nuclear hormone receptor antagonists

21 January 2018

1 reference

Protein-based virtual screening of chemical databases. 1. Evaluation of different docking/scoring combinations.

21 January 2018

1 reference

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

21 January 2018

1 reference

Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix

21 January 2018

1 reference

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

21 January 2018

1 reference

Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects

21 January 2018

1 reference

The structure of the ultraspiracle ligand-binding domain reveals a nuclear receptor locked in an inactive conformation

21 January 2018

1 reference

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

21 January 2018

1 reference

Conformational adaptation of agonists to the human nuclear receptor RAR gamma

21 January 2018

1 reference

Structural basis for isotype selectivity of the human retinoic acid nuclear receptor

21 January 2018

1 reference

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma

21 January 2018

1 reference

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

21 January 2018

1 reference

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

21 January 2018

1 reference

A structural role for hormone in the thyroid hormone receptor.

21 January 2018

1 reference

Crystal structure of the ligand binding domain of the human nuclear receptor PPARgamma

21 January 2018

1 reference

Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations

21 January 2018

1 reference

Atomic structure of progesterone complexed with its receptor

21 January 2018

1 reference

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

21 January 2018

1 reference

2-Phenylindoles. Relationship between structure, estrogen receptor affinity, and mammary tumor inhibiting activity in the rat

21 January 2018

1 reference

Distinct effects on the conformation of estrogen receptor alpha and beta by both the antiestrogens ICI 164,384 and ICI 182,780 leading to opposite effects on receptor stability

21 January 2018

1 reference

Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene

21 January 2018

1 reference

A canonical structure for the ligand-binding domain of nuclear receptors

21 January 2018

1 reference

Torsionally and hydrophobically modified 2,3-diarylindenes as estrogen receptor ligands

21 January 2018

1 reference

New approach to molecular docking and its application to virtual screening of chemical databases

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.1024

1 reference

2 August 2017

1 reference