Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex (Q34428701)

2 August 2017

title

Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex (English)

1 reference

2 August 2017

Ezgi Kunttas-Tatli

1

1 reference

2 August 2017

David M Roberts

series ordinal

2

1 reference

2 August 2017

Brooke M McCartney

series ordinal

3

1 reference

2 August 2017

publication date

10 September 2014

1 reference

Molecular Biology of the Cell

2 August 2017

published in

1 reference

2 August 2017

volume

25

1 reference

2 August 2017

issue

21

1 reference

2 August 2017

page(s)

3424-3436

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4214788/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Identification of a link between the tumour suppressor APC and the kinesin superfamily

6 July 2018

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

6 July 2018

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6 July 2018

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Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis

6 July 2018

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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

6 July 2018

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6 July 2018

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Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

6 July 2018

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Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level

6 July 2018

1 reference

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

6 July 2018

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

6 July 2018

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

6 July 2018

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Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Alternative splicing of the APC gene and its association with terminal differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

APC mutation in the alternatively spliced region of exon 9 associated with late onset familial adenomatous polyposis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Dimer formation by an N-terminal coiled coil in the APC protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Demonstration of promoter activity and alternative splicing in the region 5' to exon 1 of the APC gene.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Predicting coiled coils from protein sequences

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Identification of deletion mutations and three new genes at the familial polyposis locus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Identification and characterization of the familial adenomatous polyposis coli gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs.

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1091%2FMBC.E14-04-0885

Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1091%2FMBC.E14-04-0885

Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1091%2FMBC.E14-04-0885

Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4214788

27 October 2018

Identifiers

DOI

10.1091/MBC.E14-04-0885

1 reference

2 August 2017

1 reference

2 August 2017

1 reference