Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice (Q34430920)

2 August 2017

title

Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice (English)

1 reference

2 August 2017

9

Terrence Town

1 reference

2 August 2017

8

Jun Tan

1 reference

2 August 2017

1

Takashi Mori

1 reference

2 August 2017

Naoki Koyama

2

1 reference

2 August 2017

Tatsuya Segawa

3

1 reference

2 August 2017

Masahiro Maeda

4

1 reference

2 August 2017

Nobuhiro Maruyama

5

1 reference

2 August 2017

Noriaki Kinoshita

6

1 reference

2 August 2017

Huayan Hou

7

1 reference

2 August 2017

language of work or name

English

0 references

publication date

25 August 2014

1 reference

Journal of Biological Chemistry

2 August 2017

published in

1 reference

2 August 2017

volume

289

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2 August 2017

issue

44

1 reference

2 August 2017

page(s)

30303-30317

1 reference

Targeting the β secretase BACE1 for Alzheimer's disease therapy

2 August 2017

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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A specific amyloid-beta protein assembly in the brain impairs memory

6 July 2018

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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

6 July 2018

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beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

6 July 2018

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The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.

6 July 2018

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Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

6 July 2018

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6 July 2018

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Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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21 January 2018

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Hope in Alzheimer's fight emerges from unexpected places

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice

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Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues

21 January 2018

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Pharmacokinetics and organ distribution of intravenous and oral methylene blue.

21 January 2018

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21 January 2018

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Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish

21 January 2018

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BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

21 January 2018

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BACE1 inhibition reduces endogenous Abeta and alters APP processing in wild-type mice

21 January 2018

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Methylene blue supravital staining: an evaluation of its applicability to the mammalian brain and pineal gland

21 January 2018

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Reference dose (RfD): description and use in health risk assessments

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25157105

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.568212

1 reference

2 August 2017

1 reference

2 August 2017

1 reference