Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair (Q34438294)

2 August 2017

Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair (English)

1 reference

2 August 2017

5

0 references

Kohsuke Imai

object named as

Kohsuke Imai

series ordinal

2

0 references

Anne Durandy

object named as

Anne H Durandy

series ordinal

6

0 references

Hans D. Ochs

series ordinal

4

object named as

Hans D Ochs

1 reference

2 August 2017

3

Pauline Gardès

1 reference

2 August 2017

1

Sven Kracker

1 reference

PubMed ID

21135220

2 August 2017

language of work or name

English

0 references

publication date

6 December 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

1 reference

2 August 2017

107

1 reference

2 August 2017

51

1 reference

2 August 2017

22225-22230

1 reference

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

NHEJ and its backup pathways in chromosomal translocations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Multiple functions of MRN in end-joining pathways during isotype class switching

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

IgH class switching and translocations use a robust non-classical end-joining pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Nibrin functions in Ig class-switch recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

ATM is required for efficient recombination between immunoglobulin switch regions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Genomic instability in mice lacking histone H2AX

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009794

Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

H2AX prevents DNA breaks from progressing to chromosome breaks and translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

In situ class switching and differentiation to IgA-producing cells in the gut lamina propria

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

SnapShot: Nonhomologous DNA end joining (NHEJ).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

AID mutant analyses indicate requirement for class-switch-specific cofactors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

Rag mutations reveal robust alternative end joining

21 January 2018

2 references

https://api.crossref.org/works/10.1073%2FPNAS.1012591108

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/21135220

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21135220

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21135220

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1012591108

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference

PubMed ID

21135220