Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1 (Q34441649)

2 August 2017

title

Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1 (English)

1 reference

2 August 2017

12

Bernhard Brüne

1 reference

2 August 2017

Johanna S Blees

1

1 reference

2 August 2017

Heidi R Bokesch

2

1 reference

2 August 2017

Daniela Rübsamen

3

1 reference

2 August 2017

Kathrin Schulz

4

1 reference

2 August 2017

Larissa Milke

5

1 reference

2 August 2017

Magdalena M Bajer

6

1 reference

2 August 2017

Kirk R Gustafson

7

1 reference

2 August 2017

Curtis J Henrich

8

1 reference

2 August 2017

James B McMahon

9

1 reference

2 August 2017

Nancy H Colburn

10

1 reference

2 August 2017

Tobias Schmid

11

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2 August 2017

language of work or name

English

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publication date

2 October 2012

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2 August 2017

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2 August 2017

volume

7

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2 August 2017

issue

10

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2 August 2017

page(s)

e46567

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Creative Commons CC0 License

2 August 2017

copyright license

start time

2 October 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Loss of Programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer.

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Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

6 July 2018

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Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion

6 July 2018

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Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway

6 July 2018

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Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors

6 July 2018

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S6K1- and betaTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth

6 July 2018

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6 July 2018

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Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion

6 July 2018

1 reference

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6 July 2018

Signaling to NF-kappaB

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The SCF ubiquitin ligase: insights into a molecular machine

6 July 2018

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Associations Among -TrCP, an E3 Ubiquitin Ligase Receptor, -Catenin, and NF- B in Colorectal Cancer

6 July 2018

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6 July 2018

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Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity

6 July 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3462793

Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation.

6 July 2018

1 reference

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Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

6 July 2018

1 reference

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The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation

6 July 2018

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

6 July 2018

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A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation

6 July 2018

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Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

6 July 2018

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Siamenol, a new carbazole alkaloid from Murraya siamensis

6 July 2018

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Superoxide attenuates macrophage apoptosis by NF-kappa B and AP-1 activation that promotes cyclooxygenase-2 expression

6 July 2018

1 reference

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Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

6 July 2018

1 reference

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Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response

6 July 2018

1 reference

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β-catenin is a target for the ubiquitin–proteasome pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3462793

Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3462793

Targeting beta-transducin repeat-containing protein E3 ubiquitin ligase augments the effects of antitumor drugs on breast cancer cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3462793

Sesquiterpene lactones inhibit luciferase but not beta-galactosidase activity in vitro and ex vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3462793

Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23056346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Small-molecule inhibitors of the p53-HDM2 interaction for the treatment of cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23056346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

SnapShot: F Box Proteins II

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23056346

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0046567

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference